INT53493

Context Info Confidence 0.53 First Reported 1994 Last Reported 2010 Negated 0 Speculated 0 Reported most in Abstract Documents 3 Total Number 3 Disease Relevance 2.68 Pain Relevance 1.77

extracellular space (C6) extracellular region (C6)

Anatomy Link Frequency upper 1 C6 (Homo sapiens)

Pain Link Frequency Relevance Heat Kinase C 6 97.56 Nicotine 10 94.08 imagery 1 93.68 opioid receptor 1 91.08 Opioid 6 88.00 methadone 2 87.24 antagonist 3 85.60 Morphine 3 85.20 Pain 2 85.16 Spinal cord 3 75.00

Disease Link Frequency Relevance Heat Sprains And Strains 48 99.62 Apoptosis 8 97.76 Paralysis 2 96.80 Blister 1 96.48 Pressure And Volume Under Development 2 94.44 Lung Cancer 4 91.92 Disease 2 89.60 Cancer 2 89.04 Injury 3 87.40 Neck Pain 1 85.16

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

They also suggest complexities in the system where blockade of C6 or C10 nicotinic receptors can lead to facilitation of apoptosis.

Negative_regulation (blockade) of C6 associated with apoptosis

1) Confidence 0.53 Published 1994 Journal Cell Growth Differ. Section Abstract Doc Link 7848904 Disease Relevance 0.81 Pain Relevance 1.44

In the upper extremities he had weakness and sensory loss at the level of C6.

Negative_regulation (loss) of C6 in upper

2) Confidence 0.43 Published 2010 Journal J Emerg Med Section Abstract Doc Link 18597977 Disease Relevance 1.23 Pain Relevance 0.32

Following incubation in NHS, the two transformed strains G1/pCRASP-3 and G1/pCRASP-5 as well as G1/pKFSS1 and the wild-type strain G1 showed surface deposition of C3, C6 and C5b-9 (Fig. 7).

Negative_regulation (deposition) of C6 associated with sprains and strains

3) Confidence 0.08 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2958145 Disease Relevance 0.64 Pain Relevance 0

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