INT53502

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.34
First Reported 1994
Last Reported 2008
Negated 2
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 1.42
Pain Relevance 0.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Ppap2a) plasma membrane (Ppap2a)
Anatomy Link Frequency
blood 1
plasma 1
vessels 1
heart 1
Ppap2a (Mus musculus)
Pain Link Frequency Relevance Heat
aspirin 1 98.40 Very High Very High Very High
dexamethasone 2 94.96 High High
antagonist 1 90.96 High High
Inflammatory mediators 5 85.68 High High
headache 1 72.24 Quite High
corticosteroid 1 53.12 Quite High
withdrawal 2 44.80 Quite Low
Inflammation 4 33.20 Quite Low
cva 2 18.16 Low Low
anesthesia 7 10.00 Low Low
Disease Link Frequency Relevance Heat
Increased Venous Pressure Under Development 22 99.92 Very High Very High Very High
Disease 18 91.64 High High
INFLAMMATION 11 85.28 High High
Cv General 2 Under Development 1 84.64 Quite High
Lung Injury 10 82.88 Quite High
Pulmonary Hypertension 1 80.08 Quite High
Fever 1 73.64 Quite High
Vomiting 1 72.68 Quite High
Headache 1 72.24 Quite High
Pressure And Volume Under Development 8 67.84 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The combination of INO and dobutamine caused a significant increase in cardiac index, heart rate and SVI, without modifying either MPAP or MAP, as a result of a significant fall in pulmonary and systemic vascular resistance.
Neg (without) Regulation (modifying) of MPAP in heart
1) Confidence 0.34 Published 2001 Journal Crit Care Section Body Doc Link PMC96124 Disease Relevance 0.24 Pain Relevance 0
The combination of both drugs causes an increase in cardiac index but no change in MPAP.
Neg (no) Regulation (change) of MPAP
2) Confidence 0.21 Published 2001 Journal Crit Care Section Body Doc Link PMC96124 Disease Relevance 0.16 Pain Relevance 0
The correlation coefficient (R2) was 0.66 between changes in regional blood flow and DeltaNOE, and 0.37 between changes in MPaP and DeltaNOE.
Regulation (changes) of MPaP in blood
3) Confidence 0.04 Published 2003 Journal Acta Anaesthesiol Scand Section Body Doc Link 12648198 Disease Relevance 0 Pain Relevance 0
CONCLUSIONS: Nitric oxide concentration increases dramatically from lung regions with occluded vessels, whereas changes in MPaP have minor effects on NOE.
Regulation (changes) of MPaP in vessels
4) Confidence 0.04 Published 2003 Journal Acta Anaesthesiol Scand Section Body Doc Link 12648198 Disease Relevance 0 Pain Relevance 0
This observation may, as said above, explain higher values of the MPAP in responders.
Regulation (values) of MPAP
5) Confidence 0.04 Published 2008 Journal Crit Care Section Body Doc Link PMC2592770 Disease Relevance 0.30 Pain Relevance 0.04
Oxygent HT-induced changes in mPAP, flush, and plasma TxB were blocked by aspirin and ibuprofen.
Regulation (changes) of mPAP in plasma associated with aspirin and increased venous pressure under development
6) Confidence 0.01 Published 1994 Journal Artif Cells Blood Substit Immobil Biotechnol Section Abstract Doc Link 7849964 Disease Relevance 0.72 Pain Relevance 0.28

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox