INT53571

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Context Info
Confidence 0.50
First Reported 1994
Last Reported 1996
Negated 1
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.59
Pain Relevance 0.99

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Il1a) extracellular space (Il1a) extracellular region (Il1a)
Il1a (Mus musculus)
Pain Link Frequency Relevance Heat
Paracetamol 10 99.32 Very High Very High Very High
cytokine 3 92.52 High High
antagonist 1 83.84 Quite High
ketamine 1 62.08 Quite High
anesthesia 2 56.84 Quite High
Disease Link Frequency Relevance Heat
Fever 2 99.34 Very High Very High Very High
Hepatotoxicity 3 96.96 Very High Very High Very High
Sepsis 4 96.72 Very High Very High Very High
Endotoxemia 4 96.32 Very High Very High Very High
Necrosis 4 93.56 High High
Cancer 2 93.20 High High
Poisoning 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Hyperthermia induces IL-1 alpha but does not decrease release of IL-1 alpha or TNF-alpha after endotoxin.
Neg (not) Negative_regulation (decrease) of Localization (release) of IL-1 alpha associated with fever
1) Confidence 0.50 Published 1994 Journal Lymphokine Cytokine Res. Section Title Doc Link 7858059 Disease Relevance 0.86 Pain Relevance 0.15
Neutralization of TNF-alpha or IL-1 alpha with specific antibodies partially prevented the hepatotoxic effects of APAP at the 4- and 8-hr time points.
Negative_regulation (prevented) of Localization (Neutralization) of IL-1 alpha associated with paracetamol
2) Confidence 0.39 Published 1996 Journal Toxicol Pathol Section Abstract Doc Link 8992608 Disease Relevance 0.73 Pain Relevance 0.84

General Comments

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