INT53576

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Context Info
Confidence 0.41
First Reported 1993
Last Reported 1994
Negated 1
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.60
Pain Relevance 0.73

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Il1a) extracellular space (Il1a) extracellular region (Il1a)
Anatomy Link Frequency
macrophages 2
Blood 2
Il1a (Mus musculus)
Pain Link Frequency Relevance Heat
cocaine 2 93.36 High High
anesthesia 2 92.88 High High
methadone 2 92.88 High High
Morphine 2 92.44 High High
ketamine 1 80.64 Quite High
cytokine 2 78.08 Quite High
Disease Link Frequency Relevance Heat
Depression 1 96.56 Very High Very High Very High
Fever 2 75.48 Quite High
Endotoxemia 4 67.28 Quite High
Sepsis 4 66.68 Quite High
Communicable Diseases 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, the activity of drugs of abuse was studied on IL-1 alpha and TNF production by activated murine macrophages.
Regulation (studied) of Gene_expression (production) of IL-1 alpha in macrophages
1) Confidence 0.41 Published 1993 Journal Int. J. Immunopharmacol. Section Abstract Doc Link 8407054 Disease Relevance 0.10 Pain Relevance 0.43
Blood samples obtained after endotoxin revealed no difference in levels of TNF-alpha (5477 +/- 742 vs. 6514 +/- 652 pg/ml) or IL-1 alpha (546 +/- 72 vs. 603 +/- 121 pg/ml) in the sham vs. heated mice.
Neg (no) Regulation (difference) of Gene_expression (levels) of IL-1 alpha in Blood
2) Confidence 0.39 Published 1994 Journal Lymphokine Cytokine Res. Section Abstract Doc Link 7858059 Disease Relevance 0.50 Pain Relevance 0.30

General Comments

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