INT53587

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Context Info
Confidence 0.12
First Reported 1994
Last Reported 1994
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 2.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Adra2a) plasma membrane (Adra2a) cytoplasm (Adra2a)
signal transducer activity (Adra2a)
Anatomy Link Frequency
spinal 2
Adra2a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antinociception 5 99.64 Very High Very High Very High
Opioid 3 99.48 Very High Very High Very High
analgesia 1 99.20 Very High Very High Very High
Cholecystokinin 8 98.80 Very High Very High Very High
Morphine 2 96.60 Very High Very High Very High
antagonist 5 96.56 Very High Very High Very High
MU agonist 2 95.84 Very High Very High Very High
c fibre 4 94.12 High High
intrathecal 3 91.60 High High
Antinociceptive 2 80.68 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The results suggest CCK is able to inhibit spinal antinociception mediated via the activation of alpha 2-adrenergic receptors in addition to its well-documented interaction with spinal opioid analgesia.
Positive_regulation (activation) of alpha 2-adrenergic Binding (interaction) of in spinal associated with antinociception, opioid, cholecystokinin and analgesia
1) Confidence 0.12 Published 1994 Journal Brain Res. Section Abstract Doc Link 7859067 Disease Relevance 0 Pain Relevance 2.26

General Comments

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