INT53674

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Context Info
Confidence 0.45
First Reported 1995
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 1.48
Pain Relevance 1.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Pcsk1) extracellular space (Pcsk1) Golgi apparatus (Pcsk1)
Anatomy Link Frequency
PC-3 1
Pcsk1 (Mus musculus)
Pain Link Frequency Relevance Heat
Opioid 9 98.12 Very High Very High Very High
Dynorphin 6 91.08 High High
Enkephalin 12 88.72 High High
Pain 2 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Taxol 1 5.00 Very Low Very Low Very Low
medulla 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Prostate Cancer 47 100.00 Very High Very High Very High
Cancer 106 92.56 High High
Metastasis 49 90.44 High High
Insulinoma 6 75.00 Quite High
Apoptosis 20 65.76 Quite High
Targeted Disruption 3 57.68 Quite High
Breast Cancer 6 5.00 Very Low Very Low Very Low
Hypercalcemia 2 5.00 Very Low Very Low Very Low
Cervical Cancer 2 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition to the ubiquitously expressed furin, beta TC3 cells have abundant levels of prohormone convertase-1 (PC1) and PC2 mRNAs, but undetectable levels of PACE4 or PC5 mRNAs.
Transcription (levels) of PC1
1) Confidence 0.45 Published 1995 Journal Endocrinology Section Abstract Doc Link 7867572 Disease Relevance 0.30 Pain Relevance 0.41
In contrast to pro-Dyn mRNA, furin, PC1, and PC2 mRNA levels were not affected by 8-bromo-cAMP.
Transcription (levels) of PC1
2) Confidence 0.45 Published 1995 Journal Endocrinology Section Abstract Doc Link 7867572 Disease Relevance 0.07 Pain Relevance 0.41
In addition to the ubiquitously expressed furin, beta TC3 cells have abundant levels of prohormone convertase-1 (PC1) and PC2 mRNAs, but undetectable levels of PACE4 or PC5 mRNAs.
Transcription (levels) of prohormone convertase-1
3) Confidence 0.45 Published 1995 Journal Endocrinology Section Abstract Doc Link 7867572 Disease Relevance 0.30 Pain Relevance 0.41
Alendronate treatment has no effect on lymphangiogenesis in PC-3 prostate tumors
Transcription (tumors) of PC-3 in PC-3 associated with prostate cancer
4) Confidence 0.13 Published 2008 Journal BMC Cancer Section Body Doc Link PMC2294135 Disease Relevance 0.79 Pain Relevance 0

General Comments

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