INT53764

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Context Info
Confidence 0.75
First Reported 1995
Last Reported 2008
Negated 2
Speculated 1
Reported most in Body
Documents 5
Total Number 6
Disease Relevance 5.62
Pain Relevance 0.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (SPN) extracellular space (SPN) plasma membrane (SPN)
Anatomy Link Frequency
B-cell 1
neutrophil 1
T-cell 1
SPN (Homo sapiens)
Pain Link Frequency Relevance Heat
headache 2 92.40 High High
Pain refractory 1 81.52 Quite High
nud 1 81.08 Quite High
Crohn's disease 2 78.76 Quite High
tolerance 1 36.28 Quite Low
cINOD 3 5.00 Very Low Very Low Very Low
dexamethasone 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
local anesthetic 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 8 99.98 Very High Very High Very High
Immunoblastic Large-cell Lymphoma 4 99.52 Very High Very High Very High
Chronic Lymphoid Leukemia 16 98.52 Very High Very High Very High
Syndrome 8 97.60 Very High Very High Very High
Adhesions 4 94.96 High High
Chills 2 93.00 High High
INFLAMMATION 6 92.68 High High
Fever 3 92.68 High High
Headache 2 92.40 High High
Obesity 2 90.72 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The neoplasm expressed low-density monotypic IgM lambda, the pan-B-cell antigens CD19, CD20, and CDw75, and the CD5 and CD43 antigens.
Gene_expression (expressed) of CD43 in B-cell associated with cancer
1) Confidence 0.75 Published 1995 Journal Am. J. Clin. Pathol. Section Abstract Doc Link 7872259 Disease Relevance 1.72 Pain Relevance 0.09
The large cell immunoblastic lymphoma was of T-cell lineage, positive for the CD45RB, CD3, CD45RO, and CD43 antigens, and negative for the CD20 and CDw75 antigens.
Neg (negative) Gene_expression (positive) of CD43 in T-cell associated with immunoblastic large-cell lymphoma
2) Confidence 0.65 Published 1995 Journal Am. J. Clin. Pathol. Section Abstract Doc Link 7872259 Disease Relevance 1.76 Pain Relevance 0.09
RESULTS: Aceclofenac induced a dramatic decrease of L-selectin expression, whereas a moderate and slight decrement of CD43 and ICAM-3 expression was also observed.
Gene_expression (expression) of CD43
3) Confidence 0.49 Published 1996 Journal J. Rheumatol. Section Body Doc Link 8730134 Disease Relevance 0.13 Pain Relevance 0
METHODS: We used flow cytometry analysis to determine peripheral blood neutrophil expression of L-selectin, CD11a, CD11b, CD31, CD43, CD44, and intercellular adhesion molecule 2 (ICAM-3) surface adhesion molecules after treatment with aceclofenac, diclofenac, or dexamethasone.
Spec (determine) Gene_expression (expression) of CD43 in neutrophil
4) Confidence 0.49 Published 1996 Journal J. Rheumatol. Section Body Doc Link 8730134 Disease Relevance 0.19 Pain Relevance 0
Immunohistochemichally, the cells were positive for CD20, CD79a, CD43 and cyclin D1, but negative for CD3, CD5 and bcl-6.
Neg (negative) Gene_expression (positive) of CD43
5) Confidence 0.40 Published 2004 Journal Leuk. Lymphoma Section Abstract Doc Link 15359648 Disease Relevance 1.42 Pain Relevance 0.20
Nevertheless, they lack the expression of CD45, CD34, CD14, CD43, and of HLA-DR.
Gene_expression (expression) of CD43
6) Confidence 0.06 Published 2008 Journal J Transl Med Section Body Doc Link PMC2529267 Disease Relevance 0.41 Pain Relevance 0

General Comments

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