INT53780
From wiki-pain
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Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
Indeed, a significant association at the Avp locus was found for F2 mice with HAB grandmothers. | |||||||||||||||
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For competitive displacement of endogenous AVP and for receptor binding, slides were incubated (60 min, RT) with the AVP V1a-R antagonist 125I-lin AVP (NEX310, NEN DuPont, Boston, MA; 200 cpm/µl). | |||||||||||||||
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Antibodies to 3'-5' AVP-binding peptide bound to cells, and the binding was inhibited by excess AVP. | |||||||||||||||
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; [35], [36]) was used for hybridization with Avp. | |||||||||||||||
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For competitive displacement of endogenous AVP and for receptor binding, slides were incubated (60 min, RT) with the AVP V1a-R antagonist 125I-lin AVP (NEX310, NEN DuPont, Boston, MA; 200 cpm/µl). | |||||||||||||||
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This suggests a possible overlap of function distinct from the roles already noted and may reflect the action of Avp originating from different sources (e.g. pituitary vs. local tissue release (Gallo-Payet and Guillon 1998)), although the medullary cell type that expresses Avpr1as has yet to be identified. | |||||||||||||||
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Thus, binding of anti-3'-5'AVP-binding peptide antibodies to the AVP receptor was specific. | |||||||||||||||
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Thus, binding of anti-3'-5'AVP-binding peptide antibodies to the AVP receptor was specific. | |||||||||||||||
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Many of these modified Avp analogues display high selectivity for the Avpr1b and bind with sub-nanomolar affinities (Pena et al. 2007a) and thus could well be useful in the study of the Avp receptors in rodents; however, they may be of limited use as human therapeutics due to their peptidergic nature. | |||||||||||||||
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They showed that OT and AVP are consistently found in human umbilical arterial and venous plasma at the time of delivery. | |||||||||||||||
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Computerized molecular modeling revealed OT-GKR docking to active OTR sites and to V1a receptor of vasopressin. | |||||||||||||||
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Moreover, all of these receptors have the ability to bind AVP and/or OT with varying affinities. | |||||||||||||||
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98 to +39; bases 3020 to 3157), EBOV VP24 (? | |||||||||||||||
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In contrast, treatment of rhesus macaques with a combination of the VP24, VP35, and L PMOs showed substantial efficacy. | |||||||||||||||
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In contrast, treatment of rhesus macaques with a combination of the VP24, VP35, and L PMOs showed substantial efficacy. | |||||||||||||||
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We focused our analysis on three different areas: ION region in Vp (Fig. 6), the TREZ boundary between PNS and CNS (Fig. 7), and TG (Fig. 8), where we saw different expression patterns of BrdU staining. | |||||||||||||||
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Vasopressin-positive neurons are also recognized in the forebrain area, such as BNST and the medial amygdaloid nucleus (van Leeuwen and Caffe, 1983). | |||||||||||||||
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Vasopressin and CRH are closely linked to immune response; they also interact with pro-inflammatory cytokines. | |||||||||||||||
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The physiological significance of vasopressin in this region is unclear; however, it is possible that vasopressin in SCN influences the circadian rhythm of other brain peptides via synaptic interaction, as a pacemaker. | |||||||||||||||
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In contrast, in some cancer cells, such as small cell lung carcinoma (SCLC), the constitutive vasopressin gene expression is recognized and often causes SIADH. | |||||||||||||||
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General Comments
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