INT538

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Context Info
Confidence 0.57
First Reported 1975
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.01
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Chrna7) plasma membrane (Chrna7) cytoplasm (Chrna7)
Anatomy Link Frequency
urine 1
crest 1
Chrna7 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Sciatic nerve 1 99.20 Very High Very High Very High
dorsal root ganglion 1 95.48 Very High Very High Very High
tetrodotoxin 1 87.76 High High
anesthesia 6 46.28 Quite Low
adenocard 1 44.72 Quite Low
Eae 2 5.00 Very Low Very Low Very Low
Neurotransmitter 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 1 95.00 High High
Toxicity 2 93.28 High High
Overactive Bladder 198 89.16 High High
Diuresis 12 16.20 Low Low
Stress Incontinence 14 5.00 Very Low Very Low Very Low
Paralysis 8 5.00 Very Low Very Low Very Low
Anxiety Disorder 2 5.00 Very Low Very Low Very Low
Nociception 2 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The action of BTX was studied in cat sciatic nerves in vitro by measuring the rate of the crest outflow after injection of the L7 dorsal root ganglion with [3-H]leucine.
Protein_catabolism (action) of BTX in crest associated with ganglion cysts, dorsal root ganglion and sciatic nerve
1) Confidence 0.57 Published 1975 Journal Science Section Abstract Doc Link 46619 Disease Relevance 0.10 Pain Relevance 0.19
The lack of degradation of hemodynamic parameters in the BTX-prepared animals is consistent with the observed changes in urine flow rate and per-void volume being due to the lack of abdominal pressurization rather than systemic toxicity related to botulinum toxin.
Protein_catabolism (degradation) of BTX in urine associated with toxicity
2) Confidence 0.44 Published 2007 Journal BMC Urol Section Body Doc Link PMC1831476 Disease Relevance 0.49 Pain Relevance 0
Reinforcement of the fluid column with a small (<1 ml) bolus of saline via the intraperitoneal catheter corrected this degradation in the BTX animals.
Protein_catabolism (degradation) of BTX
3) Confidence 0.44 Published 2007 Journal BMC Urol Section Body Doc Link PMC1831476 Disease Relevance 0.43 Pain Relevance 0

General Comments

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