INT53857

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Context Info
Confidence 0.13
First Reported 1995
Last Reported 1995
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.50
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Crh, GNRH1) extracellular region (Crh, GNRH1) signal transduction (GNRH1)
cell-cell signaling (GNRH1) response to stress (Crh) cytoplasm (Crh)
Crh (Rattus norvegicus)
GNRH1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Opioid 1 73.44 Quite High
Disease Link Frequency Relevance Heat
Anovulation 9 100.00 Very High Very High Very High
Stress 2 75.00 Quite High
Eating Disorder 1 41.04 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To explain this variation in response to alprazolam, we propose that alprazolam accelerates the GnRH pacemaker in SRA women by inhibiting excessive CRH activity, which blocks the GnRH pacemaker in these women.
Negative_regulation (inhibiting) of CRH Positive_regulation (accelerates) of GnRH associated with anovulation
1) Confidence 0.13 Published 1995 Journal J. Clin. Endocrinol. Metab. Section Abstract Doc Link 7883836 Disease Relevance 0.50 Pain Relevance 0.07

General Comments

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