INT53885

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.37
First Reported 1994
Last Reported 2002
Negated 0
Speculated 1
Reported most in Abstract
Documents 2
Total Number 3
Disease Relevance 0.18
Pain Relevance 1.80

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transmembrane transport (Slc43a3)
Anatomy Link Frequency
band 2
Slc43a3 (Mus musculus)
Pain Link Frequency Relevance Heat
fluoxetine 12 99.56 Very High Very High Very High
monoamine 4 98.32 Very High Very High Very High
MU agonist 2 97.72 Very High Very High Very High
antagonist 6 95.96 Very High Very High Very High
opioid receptor 1 91.56 High High
opiate 2 87.00 High High
depression 1 83.04 Quite High
Enkephalin 4 75.00 Quite High
narcan 1 70.88 Quite High
Delta opioid receptors 1 60.24 Quite High
Disease Link Frequency Relevance Heat
Cognitive Disorder 2 96.88 Very High Very High Very High
Depression 1 83.04 Quite High
Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
When infused ICV (4.6-154 nmol/h), DPDPE elicited dose-dependent activation of fetal EEG, with a reduction in power distribution in the delta (1-4 Hz) band, and an increase in the beta (15-32 Hz) band.
Positive_regulation (elicited) of Positive_regulation (activation) of EEG in band
1) Confidence 0.37 Published 1994 Journal Pharmacol. Biochem. Behav. Section Abstract Doc Link 7886089 Disease Relevance 0.08 Pain Relevance 0.63
Here, we investigated frequency-specific EEG effects of the 5-HT re-uptake inhibitor fluoxetine (10 and 20 mg/kg) to restore EEG activation abolished by combined treatment with the monoamine depletor reserpine (10 mg/kg) and the muscarinic antagonist scopolamine (1 mg/kg).
Spec (investigated) Positive_regulation (restore) of Positive_regulation (activation) of EEG associated with antagonist, monoamine and fluoxetine
2) Confidence 0.02 Published 2002 Journal Neuropharmacology Section Abstract Doc Link 11804611 Disease Relevance 0 Pain Relevance 0.54
However, fluoxetine strongly potentiates the effectiveness of tacrine to restore EEG activation.
Positive_regulation (restore) of Positive_regulation (activation) of EEG associated with fluoxetine
3) Confidence 0.02 Published 2002 Journal Neuropharmacology Section Abstract Doc Link 11804611 Disease Relevance 0.10 Pain Relevance 0.62

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox