INT54043

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Context Info
Confidence 0.61
First Reported 1994
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 1.59
Pain Relevance 1.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Fn1) extracellular region (Fn1) cell adhesion (Fn1)
proteinaceous extracellular matrix (Fn1) extracellular matrix organization (Fn1)
Anatomy Link Frequency
plasma 1
stellate cells 1
Fn1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
chemokine 3 99.88 Very High Very High Very High
cytokine 4 99.68 Very High Very High Very High
metalloproteinase 1 98.32 Very High Very High Very High
Inflammation 7 92.68 High High
fibrosis 2 90.76 High High
alcohol 5 88.08 High High
Pain 1 87.36 High High
rheumatoid arthritis 2 82.40 Quite High
Chronic pancreatitis 6 81.28 Quite High
ketamine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 4 92.68 High High
Fibrosis 2 90.76 High High
Arthralgia 1 87.36 High High
Pancreatitis 10 85.92 High High
Rheumatoid Arthritis 2 82.40 Quite High
Injury 22 80.16 Quite High
Polymyositis 1 78.64 Quite High
Systemic Lupus Erythematosus 1 77.96 Quite High
Alcohol Addiction 1 53.32 Quite High
Diabetes Mellitus 22 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As the plasma flow in cryofiltration was 30 ml/min, a clearance of EDA(+) FN and Fbg, approximately 23 ml/min, was obviously high.
Transcription (clearance) of FN in plasma
1) Confidence 0.61 Published 1994 Journal Int J Artif Organs Section Abstract Doc Link 7896431 Disease Relevance 0.40 Pain Relevance 0.17
As illustrated in Fig. 4, AGE (50 µg/mL) treatment for 24 hours markedly increased mRNA expression for collagen type III, fibronectin, and CTGF.
Transcription (expression) of fibronectin
2) Confidence 0.12 Published 2010 Journal Korean Circulation Journal Section Body Doc Link PMC2978295 Disease Relevance 0 Pain Relevance 0
Compared with control-fed C+CsA+Cer rats, their ethanol-fed E+CsA+Cer counterparts showed marked increases in pancreatic NF-kappaB activation and cytokine/chemokine mRNA expression, collagen and fibronectin, the expression and activities of matrix metalloproteinase-2 and -9, and activation of pancreatic stellate cells.
Transcription (expression) of fibronectin in stellate cells associated with chemokine, metalloproteinase and cytokine
3) Confidence 0.06 Published 2008 Journal Am. J. Physiol. Gastrointest. Liver Physiol. Section Abstract Doc Link 17884979 Disease Relevance 1.18 Pain Relevance 0.93

General Comments

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