INT54056

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Context Info
Confidence 0.37
First Reported 1994
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.99
Pain Relevance 0.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (App) Golgi apparatus (App) plasma membrane (App)
extracellular matrix organization (App) DNA binding (App) cytoplasm (App)
App (Rattus norvegicus)
Pain Link Frequency Relevance Heat
depression 15 98.84 Very High Very High Very High
Kinase C 1 98.64 Very High Very High Very High
bradykinin 1 80.40 Quite High
Neurotransmitter 1 66.80 Quite High
tetrodotoxin 1 60.56 Quite High
agonist 1 46.24 Quite Low
Fibrositis 6 12.64 Low Low
Angina 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Asthma 11 100.00 Very High Very High Very High
Depression 15 98.84 Very High Very High Very High
Alzheimer's Dementia 3 85.44 High High
Disease 29 82.72 Quite High
Diabetes Mellitus 8 46.00 Quite Low
Coronary Artery Disease 6 21.60 Low Low
Osteoporosis 6 20.00 Low Low
Pulmonary Disease 5 13.12 Low Low
Sleep Disorders 6 12.64 Low Low
Chronic Disease 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The association between asthma and APP was reduced (odds ratio decreasing from approximately 1.5 to 1.3) but remained significant (p = 0.010).
Negative_regulation (reduced) of APP Binding (association) of associated with asthma
1) Confidence 0.37 Published 2008 Journal Environ Health Section Body Doc Link PMC2289819 Disease Relevance 0.59 Pain Relevance 0.13
Concomitantly, their activation decreases the formation of both secreted soluble beta A4 and of endosomal-lysosomal C-terminal APP derivatives.
Negative_regulation (decreases) of APP Binding (formation) of
2) Confidence 0.32 Published 1994 Journal J. Neural Transm. Suppl. Section Abstract Doc Link 7897393 Disease Relevance 0.40 Pain Relevance 0.18

General Comments

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