INT54076

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Context Info
Confidence 0.67
First Reported 1994
Last Reported 2009
Negated 0
Speculated 0
Reported most in Title
Documents 4
Total Number 5
Disease Relevance 1.65
Pain Relevance 1.98

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Adcyap1) signal transduction (Adcyap1) extracellular space (Adcyap1)
extracellular region (Adcyap1)
Anatomy Link Frequency
meningeal artery 2
lateral 1
neurons 1
Adcyap1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Calcitonin gene-related peptide 6 99.12 Very High Very High Very High
trigeminal ganglion 1 98.78 Very High Very High Very High
Neuropeptide 10 98.52 Very High Very High Very High
Migraine 4 95.56 Very High Very High Very High
amygdala 164 95.04 Very High Very High Very High
Enkephalin 2 91.52 High High
gABA 2 89.52 High High
agonist 6 80.28 Quite High
antagonist 14 73.16 Quite High
projection neuron 2 65.20 Quite High
Disease Link Frequency Relevance Heat
Ganglion Cysts 1 98.78 Very High Very High Very High
Migraine Disorders 4 95.56 Very High Very High Very High
Heart Rate Under Development 6 85.92 High High
Shock 108 82.72 Quite High
Increased Venous Pressure Under Development 1 60.56 Quite High
Anxiety Disorder 78 60.36 Quite High
Pressure And Volume Under Development 1 58.16 Quite High
Depression 1 56.48 Quite High
Nociception 1 55.36 Quite High
Urological Neuroanatomy 2 50.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Based on the high concentration of PACAP nerve fibers in the lateral, capsular subnuclei and medium density
Transcription (fibers) of PACAP in lateral
1) Confidence 0.67 Published 2007 Journal Neural Plasticity Section Body Doc Link PMC1906870 Disease Relevance 0.47 Pain Relevance 0.70
Probe burying was significantly delayed in PACAP-injected
Transcription (delayed) of PACAP
2) Confidence 0.58 Published 2007 Journal Neural Plasticity Section Body Doc Link PMC1906870 Disease Relevance 0.33 Pain Relevance 0.25
The PACAP probe labelled small to medium-sized neurons in the trigeminal ganglion and dorsal root ganglia at different levels, indicating the presence of PACAP mRNA.
Transcription (presence) of PACAP in neurons associated with ganglion cysts and trigeminal ganglion
3) Confidence 0.53 Published 1994 Journal Neuroscience Section Abstract Doc Link 7898655 Disease Relevance 0.33 Pain Relevance 0.39
The in vivo effect of VIP, PACAP-38 and PACAP-27 and mRNA expression of their receptors in rat middle meningeal artery.
Transcription (expression) of PACAP-38 in meningeal artery
4) Confidence 0.50 Published 2009 Journal Cephalalgia Section Title Doc Link 19220306 Disease Relevance 0.26 Pain Relevance 0.32
The in vivo effect of VIP, PACAP-38 and PACAP-27 and mRNA expression of their receptors in rat middle meningeal artery.
Transcription (expression) of PACAP in meningeal artery
5) Confidence 0.22 Published 2009 Journal Cephalalgia Section Title Doc Link 19220306 Disease Relevance 0.26 Pain Relevance 0.32

General Comments

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