INT5412

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Context Info
Confidence 0.62
First Reported 1982
Last Reported 2007
Negated 0
Speculated 2
Reported most in Abstract
Documents 9
Total Number 10
Disease Relevance 1.64
Pain Relevance 2.87

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (G6pd) oxidoreductase activity (G6pd) nucleus (G6pd)
carbohydrate metabolic process (G6pd) cytoplasm (G6pd)
Anatomy Link Frequency
skeletal muscle 2
Neural 2
liver 1
G6pd (Rattus norvegicus)
Pain Link Frequency Relevance Heat
corticosteroid 12 100.00 Very High Very High Very High
Analgesic 3 100.00 Very High Very High Very High
tetrodotoxin 20 98.80 Very High Very High Very High
cINOD 3 96.92 Very High Very High Very High
alcohol 1 95.84 Very High Very High Very High
dexamethasone 9 86.40 High High
Ultiva 2 84.00 Quite High
rapifen 3 80.32 Quite High
algil 2 78.00 Quite High
Paracetamol 1 58.16 Quite High
Disease Link Frequency Relevance Heat
Cataract 6 98.88 Very High Very High Very High
Injury 60 97.36 Very High Very High Very High
INFLAMMATION 7 96.72 Very High Very High Very High
Urological Neuroanatomy 17 94.48 High High
Stress 9 82.28 Quite High
Diabetes Mellitus 3 79.36 Quite High
Gallstones 13 77.00 Quite High
Cv Unclassified Under Development 2 39.72 Quite Low
Liver Disease 1 28.44 Quite Low
Pancreatitis 1 27.32 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We tested the hypothesis that glucose 6-phosphate dehydrogenase (G6PD) activity in the rat skeletal muscle is regulated by putative axonally derived neurotrophic factors.
Regulation (regulated) of glucose 6-phosphate dehydrogenase in skeletal muscle
1) Confidence 0.62 Published 1982 Journal J. Neurochem. Section Abstract Doc Link 7108545 Disease Relevance 0 Pain Relevance 0.25
We tested the hypothesis that glucose 6-phosphate dehydrogenase (G6PD) activity in the rat skeletal muscle is regulated by putative axonally derived neurotrophic factors.
Regulation (regulated) of G6PD in skeletal muscle
2) Confidence 0.62 Published 1982 Journal J. Neurochem. Section Abstract Doc Link 7108545 Disease Relevance 0 Pain Relevance 0.25
The objective of this study was to scrutinize effects of some corticosteroids on glucose-6-phosphate dehydrogenase (G6PD) and some antioxidant enzymes.
Regulation (effects) of glucose-6-phosphate dehydrogenase associated with corticosteroid
3) Confidence 0.60 Published 2005 Journal J Enzyme Inhib Med Chem Section Abstract Doc Link 15895680 Disease Relevance 0.09 Pain Relevance 0.35
The objective of this study was to scrutinize effects of some corticosteroids on glucose-6-phosphate dehydrogenase (G6PD) and some antioxidant enzymes.
Regulation (effects) of G6PD associated with corticosteroid
4) Confidence 0.60 Published 2005 Journal J Enzyme Inhib Med Chem Section Abstract Doc Link 15895680 Disease Relevance 0.09 Pain Relevance 0.36
Neural regulation of muscle glucose 6-phosphate dehydrogenase: effect of batrachotoxin and tetrodotoxin.
Regulation (regulation) of glucose 6-phosphate dehydrogenase in Neural associated with tetrodotoxin
5) Confidence 0.54 Published 1982 Journal J. Neurochem. Section Title Doc Link 7108545 Disease Relevance 0 Pain Relevance 0.33
We have investigated the effect of G-6-PD deficiency, either experimentally induced or genetically transmitted, on the sorbitol accumulation in whole cells incubated in high glucose media and on the "sugar-cataracts" formation in a galactosemic rat model.
Spec (investigated) Regulation (effect) of G-6-PD associated with cataract
6) Confidence 0.45 Published 1992 Journal Arch. Med. Res. Section Abstract Doc Link 1308788 Disease Relevance 0.42 Pain Relevance 0.11
Evaluation of effect of some corticosteroids on glucose-6-phosphate dehydrogenase and comparative study of antioxidant enzyme activities.
Regulation (effect) of glucose-6-phosphate dehydrogenase associated with corticosteroid
7) Confidence 0.44 Published 2005 Journal J Enzyme Inhib Med Chem Section Title Doc Link 15895680 Disease Relevance 0.10 Pain Relevance 0.39
These results argue for a role of axonal transport in neural regulation of muscle G6PD, with a small contribution by neuromuscular activity.
Regulation (regulation) of G6PD in neural
8) Confidence 0.24 Published 1982 Journal J. Neurochem. Section Abstract Doc Link 7108545 Disease Relevance 0 Pain Relevance 0.36
Effects of analgesic drugs on G6PD were studied on the purified enzyme (ammonium fractionation, dialysis and 2',5' ADP-Sepharose 4B affinity chromatography) for the healthy person and G6PD-deficient persons 1, 2 and 3.
Regulation (Effects) of G6PD associated with analgesic
9) Confidence 0.08 Published 2004 Journal J Enzyme Inhib Med Chem Section Abstract Doc Link 15558953 Disease Relevance 0 Pain Relevance 0.47
We also examined the effect of TJ-10 administration on the hepatic activities of antioxidant enzymes such as SOD, catalase, Se-GSHpx, GSSG-R, and glucose-6-phosphate dehydrogenase (G-6-PDH), an enzyme to produce NAPDH using glucose-6-phospahte, with liver injury progression in ANIT-treated rats.


Spec (examined) Regulation (effect) of glucose-6-phosphate in liver associated with injury
10) Confidence 0.02 Published 2007 Journal Journal of Clinical Biochemistry and Nutrition Section Body Doc Link PMC2291502 Disease Relevance 0.94 Pain Relevance 0

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