INT54178

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.39
First Reported 1993
Last Reported 1997
Negated 2
Speculated 0
Reported most in Abstract
Documents 5
Total Number 5
Disease Relevance 0.29
Pain Relevance 2.85

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (Adora1) plasma membrane (Adora1) signal transducer activity (Adora1)
Adora1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
adenocard 32 100.00 Very High Very High Very High
agonist 7 100.00 Very High Very High Very High
antagonist 5 100.00 Very High Very High Very High
Dopamine 8 97.96 Very High Very High Very High
nMDA receptor 6 92.56 High High
antinociception 5 92.56 High High
Action potential 2 88.56 High High
nMDA receptor antagonist 2 83.32 Quite High
tetrodotoxin 5 79.44 Quite High
Hippocampus 4 75.00 Quite High
Disease Link Frequency Relevance Heat
Ganglion Cysts 6 75.00 Quite High
Shock 2 68.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Neither the adenosine A1 receptor antagonist 8-cyclopentyl-1,3-dimethylxanthine (100 microM) nor the A1 adenosine receptor agonist R(-)-N6-(2-phenylisopropyl)adenosine (100 microM) affected release.
Neg (Neither) Regulation (affected) of adenosine A1 receptor associated with adenocard, antagonist and agonist
1) Confidence 0.39 Published 1997 Journal J. Neurochem. Section Abstract Doc Link 8978731 Disease Relevance 0 Pain Relevance 0.84
Neither the adenosine A1 receptor antagonist 8-cyclopentyl-1,3-dimethylxanthine (100 microM) nor the A1 adenosine receptor agonist R(-)-N6-(2-phenylisopropyl)adenosine (100 microM) affected release.
Neg (Neither) Regulation (affected) of A1 adenosine receptor associated with adenocard, antagonist and agonist
2) Confidence 0.34 Published 1997 Journal J. Neurochem. Section Abstract Doc Link 8978731 Disease Relevance 0 Pain Relevance 0.82
Hexamethonium, (100 microM) a nicotinic acetylcholine receptor antagonist, significantly reduced the release of both acetylcholine and ATP, indicating a positive feedback modulation of ACh and ATP release. 8-Cyclopentyl-1,3-dipropylxanthine (10 nM), the selective A1-adenosine receptor antagonist exhibited similar effect on the release of ATP and acetylcholine: both of them were augmented, showing that the stimulation-evoked release of ATP and acetylcholine are under the inhibitory control of A1-adenosine receptors.
Regulation (control) of A1-adenosine associated with adenocard and antagonist
3) Confidence 0.21 Published 1997 Journal Neuroscience Section Abstract Doc Link 9219952 Disease Relevance 0.29 Pain Relevance 0.29
In this study, we examined (a) the effect of formalin concentration on the action of caffeine, and (b) the relative involvement of adenosine A1 and A2 receptors in the action of caffeine.
Regulation (involvement) of adenosine A1 associated with adenocard
4) Confidence 0.20 Published 1996 Journal Eur. J. Pharmacol. Section Abstract Doc Link 8867096 Disease Relevance 0 Pain Relevance 0.26
Effects of adenosine A1 and A2 receptor activation on electrically evoked dopamine and acetylcholine release from rat striatal slices.
Regulation (Effects) of adenosine A1 associated with dopamine and adenocard
5) Confidence 0.17 Published 1993 Journal J. Pharmacol. Exp. Ther. Section Title Doc Link 7902434 Disease Relevance 0 Pain Relevance 0.64

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox