INT542

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Context Info
Confidence 0.75
First Reported 1970
Last Reported 2008
Negated 0
Speculated 1
Reported most in Abstract
Documents 14
Total Number 15
Disease Relevance 5.22
Pain Relevance 3.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Fshb) cytoplasm (Fshb)
Anatomy Link Frequency
follicle 11
hypothalamus 1
postovulatory follicle 1
ovaries 1
sperm 1
Fshb (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Ventral tegmentum 2 99.32 Very High Very High Very High
headache 11 99.08 Very High Very High Very High
Substantia nigra 1 98.44 Very High Very High Very High
antiepileptic Drug 2 98.24 Very High Very High Very High
Migraine 17 98.12 Very High Very High Very High
narcan 10 97.12 Very High Very High Very High
amygdala 2 96.24 Very High Very High Very High
Nucleus accumbens 2 94.52 High High
Dopamine 6 93.12 High High
Enkephalin 5 92.00 High High
Disease Link Frequency Relevance Heat
Headache 24 99.08 Very High Very High Very High
Cancer 7 99.02 Very High Very High Very High
Insulin Resistance 3 98.32 Very High Very High Very High
Delayed Puberty 1 96.08 Very High Very High Very High
Sprains And Strains 3 93.96 High High
Syndrome 3 93.80 High High
Hypoactive Sexual Desire Disorder 3 91.44 High High
Endometriosis (extended) 5 90.56 High High
Increased Venous Pressure Under Development 9 89.68 High High
Congenital Anomalies 2 88.96 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The pituitary produces luteinizing hormone and follicle stimulating hormone and the ovaries secrete estrogen and progesterone.
Gene_expression (produces) of follicle stimulating hormone in ovaries
1) Confidence 0.75 Published 1977 Journal Homemak Mag Section Abstract Doc Link 12308626 Disease Relevance 0 Pain Relevance 0
Diestrus serum levels of luteinizing hormone (LH), follicle stimulating hormone and prolactin (PRL) were also determined.
Spec (determined) Gene_expression (levels) of follicle stimulating hormone in follicle
2) Confidence 0.39 Published 1984 Journal Peptides Section Abstract Doc Link 6095222 Disease Relevance 0 Pain Relevance 0.84
To characterize partially the endocrine system in this rat, serum levels of prolactin (Prl), luteinizing hormone (LH), follicle-stimulating hormone (FSH), testosterone and corticosterone were quantified.
Gene_expression (levels) of follicle-stimulating hormone in follicle
3) Confidence 0.38 Published 1983 Journal Biol. Reprod. Section Abstract Doc Link 6403064 Disease Relevance 0.44 Pain Relevance 0.12
Compared to the controls, prolactin levels in the tumor-bearing rats had increased 70-fold, whereas the levels of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) decreased to 20 and 27%, respectively.
Gene_expression (levels) of follicle-stimulating hormone in follicle associated with cancer
4) Confidence 0.38 Published 1987 Journal Neuroendocrinology Section Abstract Doc Link 3114662 Disease Relevance 0.66 Pain Relevance 0.24
A detailed analysis was made of circulating luteinizing hormone (LH), follicle-stimulating hormone (FSH), and prolactin throughout the estrous cycle in rats.
Gene_expression (made) of follicle-stimulating hormone in follicle
5) Confidence 0.38 Published 1970 Journal Fed. Proc. Section Abstract Doc Link 5529888 Disease Relevance 0.08 Pain Relevance 0.08
Plasma levels of follicle-stimulating hormone (F.S.H.), luteinising hormone (L.H.), prolactin, oestrogen, and progesterone were measured in all.
Gene_expression (levels) of follicle-stimulating hormone in follicle
6) Confidence 0.14 Published 1975 Journal Lancet Section Abstract Doc Link 47017 Disease Relevance 1.38 Pain Relevance 0.96
The drug combination caused a measurable suppression of follicle stimulating hormone levels in both castrated does and during the postovulatory follicle stimulating hormone surge in mated rabbits.
Gene_expression (levels) of follicle stimulating hormone in postovulatory follicle
7) Confidence 0.12 Published 1982 Journal Lab. Anim. Sci. Section Abstract Doc Link 6819406 Disease Relevance 0 Pain Relevance 0.23
Serum levels of luteinizing hormone, follicle stimulating hormone, prolactin, estradiol, and progesterone were measured.
Gene_expression (levels) of follicle stimulating hormone in follicle
8) Confidence 0.11 Published 1999 Journal Int J Fertil Womens Med Section Body Doc Link 10569454 Disease Relevance 0.09 Pain Relevance 0
Norplant achieves its contraceptive effect by inhibiting the positive feedback exercised by estradiol on the hypothalamus and thus reducing levels of luteinizing hormone and follicle stimulating hormone, by rendering the cervical mucus inhospitable to passage of sperm, and by altering the composition of the endometrial tissue.
Gene_expression (levels) of follicle stimulating hormone in sperm
9) Confidence 0.11 Published 1992 Journal Profamilia Section Abstract Doc Link 12286384 Disease Relevance 0.41 Pain Relevance 0.13
This study reports the plasma levels of follicle stimulating hormone, luteinising hormone, oestradiol and testosterone in 43 women who had undergone bilateral oöphorectomy.
Gene_expression (levels) of follicle stimulating hormone in follicle
10) Confidence 0.11 Published 1978 Journal Aust N Z J Obstet Gynaecol Section Abstract Doc Link 283784 Disease Relevance 0.15 Pain Relevance 0.09
Follicle-stimulating hormone, luteinizing hormone, and prolactin levels were 118.7 +/- 5.3 mIU/ml, 118.7 +/- 9.5 mIU/ml, and 9.2 +/- 0.7 ng/ml, respectively, with no significant change after naloxone administration in untreated women.
Gene_expression (levels) of Follicle-stimulating hormone in Follicle associated with narcan
11) Confidence 0.10 Published 1986 Journal Am. J. Obstet. Gynecol. Section Abstract Doc Link 3024488 Disease Relevance 0 Pain Relevance 0.16
In valproate treated men significantly lower follicle stimulating hormone and luteinizing hormone concentrations, and free/total carnitine ratio, and higher dehydroepiandrosterone concentration can be detected.
Gene_expression (detected) of follicle stimulating hormone in follicle
12) Confidence 0.10 Published 2007 Journal Ideggyogy Sz Section Abstract Doc Link 17432088 Disease Relevance 0.45 Pain Relevance 0.09
Both the LH and the FSH profiles are thought secondary to a fundamental increase in GnRH from the hypothalamus which ultimately favors the gene expression of LHb over FSHb (Azziz et al 2006).
Gene_expression (expression) of FSHb in hypothalamus
13) Confidence 0.07 Published 2008 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2504056 Disease Relevance 1.15 Pain Relevance 0
It was shown that while serum T and prolactin (PRL) were similar between young and elderly groups, mean serum luteinizing hormone (LH) and follicle-stimulating hormone (FSH) concentrations significantly differed below and over 65 years (5.2 and 8.7 mIU/mL vs 11.0 and 18.9 mIU/mL, respectively; p<0.01).
Gene_expression (mean) of follicle-stimulating hormone in follicle
14) Confidence 0.05 Published 2006 Journal Clinical Interventions in Aging Section Body Doc Link PMC2699638 Disease Relevance 0.41 Pain Relevance 0
In oral contraceptive users (n = 5) basal plasma follicle-stimulating hormone (3.7 +/- 0.4 mIU/ml) and luteinizing hormone (3.2 +/- 0.5 mIU/ml) levels were significantly lower than in control subjects during both follicular (10.7 +/- 0.9 and 16.7 +/- 2.0) and luteal (7.7 +/- 1.4 and 10.0 +/- 0.9, respectively) phases (p less than 0.05 to 0.001).
Gene_expression (lower) of follicle-stimulating hormone in follicle
15) Confidence 0.02 Published 1986 Journal Am. J. Obstet. Gynecol. Section Abstract Doc Link 3080893 Disease Relevance 0 Pain Relevance 0.30

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