INT5423

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Context Info
Confidence 0.72
First Reported 1988
Last Reported 1992
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 0
Pain Relevance 0.94

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

enzyme regulator activity (CPN2) extracellular region (CPN2)
Anatomy Link Frequency
stomach 2
stomach wall 1
CPN2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Neuropeptide 12 99.98 Very High Very High Very High
Enkephalin 10 99.84 Very High Very High Very High
opioid receptor 1 87.68 High High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The gastric carboxypeptidase released from gastric mast cells upon degranulation may act to degrade and inactivate neuropeptides in the stomach wall.
Protein_catabolism (degrade) of carboxypeptidase in stomach wall associated with neuropeptide
1) Confidence 0.72 Published 1992 Journal Gastroenterology Section Abstract Doc Link 1309362 Disease Relevance 0 Pain Relevance 0.20
Isolation of a neuropeptide-degrading carboxypeptidase from the human stomach.
Protein_catabolism (degrading) of carboxypeptidase in stomach associated with neuropeptide
2) Confidence 0.47 Published 1992 Journal Gastroenterology Section Title Doc Link 1309362 Disease Relevance 0 Pain Relevance 0.22
The aim of this investigation was to isolate and characterize a neuropeptide-degrading carboxypeptidase from the muscular and mucosal layers of the human stomach.
Protein_catabolism (degrading) of carboxypeptidase in stomach associated with neuropeptide
3) Confidence 0.47 Published 1992 Journal Gastroenterology Section Abstract Doc Link 1309362 Disease Relevance 0 Pain Relevance 0.14
Enkephalins are short lived peptides which are rapidly cleaved by 2 membrane peptidases: an enkephalinase and a carboxypeptidase.
Protein_catabolism (cleaved) of carboxypeptidase associated with enkephalin
4) Confidence 0.09 Published 1988 Journal Gastroenterol. Clin. Biol. Section Abstract Doc Link 3220232 Disease Relevance 0 Pain Relevance 0.39

General Comments

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