INT54239

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Context Info
Confidence 0.21
First Reported 1993
Last Reported 1993
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0.54

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peptidase activity (Mme) extracellular region (Nts) plasma membrane (Mme)
Mme (Rattus norvegicus)
Nts (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Neuropeptide 6 100.00 Very High Very High Very High
Enkephalin 2 100.00 Very High Very High Very High
Nucleus accumbens 4 86.24 High High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Neutral endopeptidase 24.11 (NEP) is known to metabolize a variety of neuropeptide substrates, including the enkephalins and neurotensin, thus modifying or terminating the bioactivity of such peptides.
NEP Binding (metabolize) of neurotensin associated with neuropeptide and enkephalin
1) Confidence 0.21 Published 1993 Journal Peptides Section Abstract Doc Link 7904340 Disease Relevance 0 Pain Relevance 0.27
Neutral endopeptidase 24.11 (NEP) is known to metabolize a variety of neuropeptide substrates, including the enkephalins and neurotensin, thus modifying or terminating the bioactivity of such peptides.
endopeptidase 24.11 Binding (metabolize) of neurotensin associated with neuropeptide and enkephalin
2) Confidence 0.21 Published 1993 Journal Peptides Section Abstract Doc Link 7904340 Disease Relevance 0 Pain Relevance 0.27

General Comments

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