INT5431

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.75
First Reported 1984
Last Reported 2008
Negated 1
Speculated 0
Reported most in Body
Documents 23
Total Number 28
Disease Relevance 6.53
Pain Relevance 7.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

carbohydrate metabolic process (Glb1) lysosome (Glb1)
Anatomy Link Frequency
spinal cord 2
ventricle 1
hepatocytes 1
Spinal cord segments 1
meninges 1
Glb1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Nerve growth factor 13 99.24 Very High Very High Very High
Spinal cord 245 99.20 Very High Very High Very High
analgesia 6 97.80 Very High Very High Very High
Inflammation 441 97.32 Very High Very High Very High
intrathecal 352 94.64 High High
Cholecystokinin 14 93.88 High High
allodynia 264 93.12 High High
Neuropeptide 2 92.52 High High
Opioid 3 92.00 High High
Sciatic nerve 165 91.88 High High
Disease Link Frequency Relevance Heat
Cytomegalovirus Infection 72 99.46 Very High Very High Very High
Sprains And Strains 2 97.36 Very High Very High Very High
INFLAMMATION 454 97.32 Very High Very High Very High
Epilepsy 6 96.36 Very High Very High Very High
Pulmonary Disease 6 95.36 Very High Very High Very High
Asthma 6 95.00 High High
Neuropathic Pain 770 94.96 High High
Heart Rate Under Development 12 92.20 High High
Pseudorabies 1 92.20 High High
Targeted Disruption 7 91.44 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, voltage-dependent Drosophila Shaker H4 K+ channels and Escherichia coli beta-galactosidase were expressed efficiently in all four cell types with VV vectors.
Gene_expression (expressed) of beta-galactosidase
1) Confidence 0.75 Published 1992 Journal J. Neurosci. Section Abstract Doc Link 1309573 Disease Relevance 0.08 Pain Relevance 0.11
In the Adbetagal-infected rats, the local expression of beta-galactosidase was confirmed by X-Gal staining, and beta-galactosidase activity was quantified using a colorimetric assay.
Gene_expression (expression) of beta-galactosidase
2) Confidence 0.55 Published 2004 Journal Methods Mol. Biol. Section Abstract Doc Link 15199246 Disease Relevance 0 Pain Relevance 0.13
In the Ad beta gal-treated rats, the local expression of beta-galactosidase was confirmed by X-Gal staining, and beta-galactosidase activity was quantified using a colorimetric assay.
Gene_expression (expression) of beta-galactosidase
3) Confidence 0.55 Published 2001 Journal Ann. N. Y. Acad. Sci. Section Abstract Doc Link 11458677 Disease Relevance 0 Pain Relevance 0.09
PRV-152, a strain that expresses enhanced green fluorescent protein, was injected into sympathectomized gastrocnemius muscle, while PRV-BaBlu, which expresses beta-galactosidase, was injected into the adrenal gland in the same animals.
Gene_expression (expresses) of beta-galactosidase in adrenal gland associated with sprains and strains
4) Confidence 0.35 Published 2006 Journal J. Comp. Neurol. Section Abstract Doc Link 17072838 Disease Relevance 0.34 Pain Relevance 0.41
Similar administration of plasmid expressing beta-galactosidase indicated that the vector mainly transfected ependymal cells lining the ventricle and pia mater cells.
Gene_expression (expressing) of beta-galactosidase in ventricle
5) Confidence 0.34 Published 1997 Journal Neuroscience Section Abstract Doc Link 9044370 Disease Relevance 0.41 Pain Relevance 0.86
Expression of NGF led to bladder overactivity, whereas beta-galactosidase expression was without effect.
Gene_expression (expression) of beta-galactosidase in bladder associated with nerve growth factor
6) Confidence 0.32 Published 2004 Journal J Pain Section Abstract Doc Link 15106127 Disease Relevance 0.47 Pain Relevance 0.86
While this herpesvirus NSE vector was capable of introducing novel functional genetic information into postmitotic neurons within defined neuroanatomic constraints, the numbers of neurons expressing detectable levels of beta-galactosidase was minimal.
Gene_expression (expressing) of beta-galactosidase in neurons
7) Confidence 0.30 Published 1993 Journal Cell. Mol. Neurobiol. Section Abstract Doc Link 8111822 Disease Relevance 0.18 Pain Relevance 0.09
One week after the avulsion and treatment with AxCALacZ, the animals showed expression of beta-galactosidase activity in lesioned spinal motoneurons.
Gene_expression (expression) of beta-galactosidase in spinal
8) Confidence 0.26 Published 2000 Journal J. Neurosci. Res. Section Abstract Doc Link 10797554 Disease Relevance 0.25 Pain Relevance 0.08
Similar administration of plasmid expressing beta-galactosidase indicated that the vector mainly transfected ependymal cells lining the ventricle and pia mater cells.
Gene_expression (expressing) of beta-galactosidase in pia mater
9) Confidence 0.12 Published 1997 Journal Neuroscience Section Abstract Doc Link 9044370 Disease Relevance 0.41 Pain Relevance 0.86
Approximately 95% of hepatocytes expressed the beta-galactosidase transgene following administration of AdlacZ and PEGAd (Figure 8B and 8C).
Gene_expression (expressed) of beta-galactosidase in hepatocytes
10) Confidence 0.10 Published 2008 Journal Virol J Section Body Doc Link PMC2565663 Disease Relevance 0.18 Pain Relevance 0
Complete inactivation of the AdlacZ vector was confirmed by the absence of beta-galactosidase expression in tissues isolated from animals given UVAd.
Gene_expression (expression) of beta-galactosidase
11) Confidence 0.10 Published 2008 Journal Virol J Section Body Doc Link PMC2565663 Disease Relevance 0.13 Pain Relevance 0
MATERIAL AND METHODS: Recombinant adenovirus constructs carrying the Escherichia coli beta-galactosidase gene (Adbeta-gal) or the rat IL-4 gene (AdrIL-4) were injected into the left gastric artery of healthy LEW.1W rats.
Gene_expression (carrying) of beta-galactosidase gene in gastric artery
12) Confidence 0.09 Published 2005 Journal Scand. J. Gastroenterol. Section Body Doc Link 16165721 Disease Relevance 0 Pain Relevance 0
Maximal expression of two typical lysosomal hydrolases, N-acetyl-beta-hexosaminidase and beta-galactosidase, occurred between 18 and 21 h following release (S phase), declining to G1 phase levels during the peak of N-acetylgalactosamine (GalNAc) transferase activity.
Gene_expression (expression) of beta-galactosidase
13) Confidence 0.08 Published 1984 Journal J. Neurochem. Section Abstract Doc Link 6422000 Disease Relevance 0.18 Pain Relevance 0.23
WT (VR-5, ATCC, Manassas, VA) and first generation recombinant adenovirus 5 expressing the E. coli beta-galactosidase transgene under the control of a CMV promoter (AdlacZ) were amplified in 293 cells.
Gene_expression (expressing) of beta-galactosidase associated with cytomegalovirus infection
14) Confidence 0.08 Published 2008 Journal Virol J Section Body Doc Link PMC2565663 Disease Relevance 0.15 Pain Relevance 0
Recombinant adenovirus 5 expressing beta-galactosidase was inactivated by a method unique to our laboratory as described [53].
Gene_expression (expressing) of beta-galactosidase
15) Confidence 0.08 Published 2008 Journal Virol J Section Body Doc Link PMC2565663 Disease Relevance 0.15 Pain Relevance 0
A first generation adenoviral vector, expressing the E. coli beta-galactosidase transgene (AdlacZ) was included as an important control for direct comparison of results previously reported to those obtained from animals treated with the other modified vectors [9,10].
Gene_expression (expressing) of beta-galactosidase
16) Confidence 0.08 Published 2008 Journal Virol J Section Body Doc Link PMC2565663 Disease Relevance 0.24 Pain Relevance 0
Adenovirus expressing beta-galactosidase was prepared as described above.
Gene_expression (expressing) of beta-galactosidase
17) Confidence 0.08 Published 2008 Journal Virol J Section Body Doc Link PMC2565663 Disease Relevance 0.18 Pain Relevance 0
Rats (n = 3) were injected intrathecally with AAV2 (approximately 4.1 × 10^8 infectious particles in 10 ul) engineered to express beta-galactosidase 8 days prior to tissue fixation for beta-galactosidase histochemistry.
Gene_expression (express) of beta-galactosidase
18) Confidence 0.07 Published 2005 Journal Mol Pain Section Body Doc Link PMC1079940 Disease Relevance 0.21 Pain Relevance 0.37
A replication-defective AAV expression vector (serotype II) containing the cDNA encoding LacZ, driven by the CMV promoter that directs the expression of beta-galactosidase was obtained from Avigen (Alameda, CA.
Gene_expression (expression) of beta-galactosidase associated with cytomegalovirus infection
19) Confidence 0.07 Published 2005 Journal Mol Pain Section Body Doc Link PMC1079940 Disease Relevance 0.31 Pain Relevance 0
In contrast, clear beta-galactosidase expression was observed in LacZ injected rats (Fig. 1B), as indicated by stained cells in the pial meningeal layer.
Gene_expression (expression) of beta-galactosidase
20) Confidence 0.07 Published 2005 Journal Mol Pain Section Body Doc Link PMC1079940 Disease Relevance 0.32 Pain Relevance 0.39

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox