INT54329

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Context Info
Confidence 0.44
First Reported 1993
Last Reported 2004
Negated 1
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.17
Pain Relevance 1.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Cnp) plasma membrane (Cnp) intracellular (Cnp)
kinase activity (Cnp) cytoplasm (Cnp)
Anatomy Link Frequency
MACH 1
Cnp (Mus musculus)
Pain Link Frequency Relevance Heat
Opioid 8 99.82 Very High Very High Very High
Morphine 6 99.60 Very High Very High Very High
analgesia 2 98.60 Very High Very High Very High
Analgesic 2 75.68 Quite High
Enkephalin 1 72.76 Quite High
opiate 1 69.76 Quite High
Disease Link Frequency Relevance Heat
Nociception 1 90.24 High High
Aging 1 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Here, we have extended these studies to show an induction of analgesia in mice equivalent to a moderate dose of morphine (5 mg/kg), and the effect of both Cnp exposure and morphine injection on some open-field activity.
Regulation (effect) of Cnp associated with morphine and analgesia
1) Confidence 0.44 Published 2004 Journal Neurosci. Lett. Section Abstract Doc Link 14698475 Disease Relevance 0.09 Pain Relevance 0.92
GS activity was markedly increased in MACH cultures grown in the presence of opioids with no changes in CNP.
Neg (no) Regulation (changes) of CNP in MACH associated with opioid
2) Confidence 0.23 Published 1993 Journal J. Neurosci. Res. Section Abstract Doc Link 7908340 Disease Relevance 0.07 Pain Relevance 0.69

General Comments

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