INT54330

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Context Info
Confidence 0.69
First Reported 1993
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.15
Pain Relevance 0.89

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Cnp) plasma membrane (Cnp) intracellular (Cnp)
kinase activity (Cnp) cytoplasm (Cnp)
Cnp (Mus musculus)
Pain Link Frequency Relevance Heat
Opioid 8 98.72 Very High Very High Very High
metalloproteinase 29 98.64 Very High Very High Very High
Enkephalin 1 88.28 High High
Nerve growth factor 7 79.80 Quite High
Pain 7 5.00 Very Low Very Low Very Low
bradykinin 7 5.00 Very Low Very Low Very Low
cva 7 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Aging 1 75.00 Quite High
Coagulation Disorder 9 73.12 Quite High
Hemorrhage 9 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 8 5.00 Very Low Very Low Very Low
Bites And Stings 7 5.00 Very Low Very Low Very Low
Pain 7 5.00 Very Low Very Low Very Low
Hypotension 7 5.00 Very Low Very Low Very Low
Necrosis 6 5.00 Very Low Very Low Very Low
Natriuresis 5 5.00 Very Low Very Low Very Low
Anaerobic Bacterial Infections 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We found that CNP activity was markedly increased in the early passage following opioid treatment, indicative of a shift to oligodendrocytic expression.
Positive_regulation (increased) of CNP associated with opioid
1) Confidence 0.69 Published 1993 Journal J. Neurosci. Res. Section Abstract Doc Link 7908340 Disease Relevance 0.07 Pain Relevance 0.72
The proportion of BPP/CNP transcripts in B. alternatus was similar to B. atrox and B. jararaca but about half that of B. insularis, while serine proteinases and C-type lectins were generally less abundant than in other Bothrops species.
Positive_regulation (proportion) of CNP
2) Confidence 0.03 Published 2010 Journal BMC Genomics Section Body Doc Link PMC3017861 Disease Relevance 0.07 Pain Relevance 0.17

General Comments

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