INT54355

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Context Info
Confidence 0.61
First Reported 1994
Last Reported 2009
Negated 1
Speculated 0
Reported most in Abstract
Documents 6
Total Number 6
Disease Relevance 0.28
Pain Relevance 3.02

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (Slc6a3) plasma membrane (Slc6a3) transmembrane transport (Slc6a3)
Anatomy Link Frequency
juvenile 1
brain 1
forebrain 1
midbrain 1
Slc6a3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Dopamine 43 100.00 Very High Very High Very High
dopamine receptor 8 99.56 Very High Very High Very High
Cholecystokinin 6 99.04 Very High Very High Very High
cocaine 19 98.94 Very High Very High Very High
Enkephalin 6 98.76 Very High Very High Very High
Morphine 8 93.92 High High
midbrain 4 93.92 High High
Ventral tegmentum 2 92.24 High High
Substantia nigra 2 91.16 High High
agonist 1 86.72 High High
Disease Link Frequency Relevance Heat
Eating Disorder 3 98.48 Very High Very High Very High
Disease 3 5.00 Very Low Very Low Very Low
Stress 3 5.00 Very Low Very Low Very Low
Obesity 2 5.00 Very Low Very Low Very Low
Drug Dependence 2 5.00 Very Low Very Low Very Low
Sprains And Strains 1 5.00 Very Low Very Low Very Low
Neurological Disease 1 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low
Schizophrenia 1 5.00 Very Low Very Low Very Low
Cognitive Disorder 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Mapping of brain regions in saline control rats agreed with previous studies, including showing the presence of low abundance TH mRNA and the absence of DAT mRNA in the caudate-putamen.
Neg (absence) Transcription (absence) of DAT mRNA in brain
1) Confidence 0.61 Published 2003 Journal Brain Res. Mol. Brain Res. Section Abstract Doc Link 12654507 Disease Relevance 0 Pain Relevance 0.89
The cell surface and total expression of DAT was presented as the colorimetric readings under nonpermeabilized and permeabilized conditions and then normalized to the control groups (transfected with DAT alone) respectively.


Transcription (presented) of DAT
2) Confidence 0.57 Published 2009 Journal Mol Brain Section Body Doc Link PMC2687442 Disease Relevance 0 Pain Relevance 0
The mRNA levels of D2R and DAT in mPFC were determined with in situ hybridization.
Transcription (levels) of DAT
3) Confidence 0.49 Published 2008 Journal Zhong Nan Da Xue Xue Bao Yi Xue Ban Section Body Doc Link 18812656 Disease Relevance 0 Pain Relevance 0
In the present animal model, cocaine exposure in utero had no significant effect on mRNA levels of the dopamine transporter, D1 or D2 dopamine receptors, enkephalin, tyrosine hydroxylase, or cholecystokinin in juvenile rats.
Transcription (levels) of dopamine transporter in juvenile associated with dopamine, dopamine receptor, enkephalin, cholecystokinin and cocaine
4) Confidence 0.25 Published 1994 Journal Brain Res. Mol. Brain Res. Section Abstract Doc Link 7909578 Disease Relevance 0.08 Pain Relevance 0.73
Levels of mRNA for the dopamine transporter, tyrosine hydroxylase, cholecystokinin, D1 and D2 dopamine receptors and enkephalin were quantitated in relevant dopaminergic regions of forebrain and midbrain of offspring that were sacrificed on postnatal day 21.
Transcription (Levels) of dopamine transporter in forebrain associated with dopamine, dopamine receptor, midbrain, enkephalin and cholecystokinin
5) Confidence 0.18 Published 1994 Journal Brain Res. Mol. Brain Res. Section Abstract Doc Link 7909578 Disease Relevance 0.10 Pain Relevance 0.70
Levels of mRNA for the dopamine transporter, tyrosine hydroxylase, cholecystokinin, D1 and D2 dopamine receptors and enkephalin were quantitated in relevant dopaminergic regions of forebrain and midbrain of offspring that were sacrificed on postnatal day 21.
Transcription (Levels) of dopamine transporter in midbrain associated with dopamine, dopamine receptor, midbrain, enkephalin and cholecystokinin
6) Confidence 0.06 Published 1994 Journal Brain Res. Mol. Brain Res. Section Abstract Doc Link 7909578 Disease Relevance 0.10 Pain Relevance 0.70

General Comments

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