INT54616

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Context Info
Confidence 0.24
First Reported 1994
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 3.02
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
L1210 1
Babr (Mus musculus)
Pain Link Frequency Relevance Heat
vincristine 7 99.70 Very High Very High Very High
lidocaine 1 54.56 Quite High
Action potential 1 25.00 Low Low
Sciatic nerve 1 25.00 Low Low
Calcium channel 1 25.00 Low Low
Pain 5 5.00 Very Low Very Low Very Low
abdominal pain 2 5.00 Very Low Very Low Very Low
pruritus 2 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 93 99.72 Very High Very High Very High
Infection 213 98.40 Very High Very High Very High
Babesiosis 94 95.88 Very High Very High Very High
Protozoal Infection 4 94.44 High High
Fever 20 79.36 Quite High
Leishmaniasis 44 74.16 Quite High
Anaemia 4 68.72 Quite High
Congenital Anomalies 4 59.60 Quite High
Thrombocytopenia 4 50.32 Quite High
Brucella Infection 7 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Small Theileria annae, a Babesia microti-like piroplasm [20] endemic in northwestern Spain [21], and Babesia gibsoni have also been detected as agents of babesial disease in European dogs [22-24].
Gene_expression (detected) of Babesia associated with disease
1) Confidence 0.24 Published 2010 Journal Parasit Vectors Section Body Doc Link PMC2865458 Disease Relevance 0.71 Pain Relevance 0
However, both puppies were found infested with ticks (species not identified), which should be regarded as the most likely source of transmitting Babesia to them.
Gene_expression (source) of Babesia
2) Confidence 0.24 Published 2010 Journal Parasit Vectors Section Body Doc Link PMC2865458 Disease Relevance 0.71 Pain Relevance 0
A second study that similarly examined the transcript and proteomic alterations due to a deletion in babR corresponded with 6 genes identified in our study: with 2 genes found to be unique to the addition of C12-HSL in the ?
Gene_expression (deletion) of babR
3) Confidence 0.21 Published 2010 Journal BMC Microbiol Section Body Doc Link PMC2898763 Disease Relevance 0 Pain Relevance 0
This cell line was obtained by long-term adaptation of the L1210 mouse leukaemic cell line on vincristine and showed an overexpression of P-glycoprotein and accompanying multidrug resistance (MDR) which was defined as a cell resistance to several cytostatics such as vincristine, vinblastine and actinomycin D.
Gene_expression (overexpression) of resistance in L1210 associated with vincristine
4) Confidence 0.06 Published 1994 Journal Drugs Exp Clin Res Section Abstract Doc Link 7924890 Disease Relevance 0 Pain Relevance 0.24
This disease is caused by Babesia vogeli (= Babesia canis vogeli) (Piroplasmida: Babesiidae) (Fig. 1), which has recently been molecularly characterized in Brazil [13].
Gene_expression (vogeli) of Babesia associated with disease
5) Confidence 0.03 Published 2008 Journal Parasit Vectors Section Body Doc Link PMC2533296 Disease Relevance 0.80 Pain Relevance 0
This disease is caused by Babesia vogeli (= Babesia canis vogeli) (Piroplasmida: Babesiidae) (Fig. 1), which has recently been molecularly characterized in Brazil [13].
Gene_expression (vogeli) of Babesia associated with disease
6) Confidence 0.03 Published 2008 Journal Parasit Vectors Section Body Doc Link PMC2533296 Disease Relevance 0.80 Pain Relevance 0

General Comments

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