INT5466

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Context Info
Confidence 0.44
First Reported 1992
Last Reported 2001
Negated 0
Speculated 1
Reported most in Abstract
Documents 2
Total Number 3
Disease Relevance 0.17
Pain Relevance 1.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

generation of precursor metabolites and energy (ADRB3) aging (ADRB3) plasma membrane (ADRB3)
nucleus (ADRB3) carbohydrate metabolic process (ADRB3) signal transducer activity (ADRB3)
Anatomy Link Frequency
lymphocytes 2
ADRB3 (Homo sapiens)
Pain Link Frequency Relevance Heat
opioid receptor 1 100.00 Very High Very High Very High
Opioid 4 94.64 High High
Dopamine 1 93.36 High High
anesthesia 10 88.16 High High
adenocard 1 84.88 Quite High
epidural 2 84.44 Quite High
Morphine 2 80.96 Quite High
narcan 1 74.00 Quite High
Disease Link Frequency Relevance Heat
Pressure Volume 2 Under Development 1 96.64 Very High Very High Very High
Pyloric Stenosis 1 72.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Cardiac surgery causes desensitization of the beta-adrenergic receptor system of human lymphocytes.
Positive_regulation (causes) of Negative_regulation (desensitization) of beta-adrenergic receptor in lymphocytes
1) Confidence 0.44 Published 1992 Journal Anesth. Analg. Section Title Doc Link 1309962 Disease Relevance 0 Pain Relevance 0.54
We speculate that the down-regulation of beta-adrenoceptor induced by the sympathomimetic action of amphetamine, might be a major cause of refractory hypotension.
Positive_regulation (induced) of Negative_regulation (down-regulation) of beta-adrenoceptor associated with pressure volume 2 under development
2) Confidence 0.41 Published 2001 Journal Masui Section Abstract Doc Link 11758335 Disease Relevance 0.17 Pain Relevance 0.37
The responses were also examined in the presence of opioid receptor blocker, nitric oxide synthase inhibitor, beta-adrenoceptor blocker, or cyclooxygenase inhibitor.
Spec (examined) Positive_regulation (presence) of Negative_regulation (inhibitor) of beta-adrenoceptor associated with opioid receptor
3) Confidence 0.30 Published 2001 Journal Anesth. Analg. Section Abstract Doc Link 11273940 Disease Relevance 0 Pain Relevance 0.48

General Comments

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