INT54757

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Context Info
Confidence 0.04
First Reported 1994
Last Reported 1994
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0
Pain Relevance 0.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Vom1r1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Morphine 4 84.48 Quite High
tail-flick 2 83.20 Quite High
agonist 3 82.44 Quite High
Antinociceptive 1 79.04 Quite High
opioid receptor 1 75.00 Quite High
antagonist 2 74.08 Quite High
narcan 1 70.00 Quite High
Opioid 1 61.00 Quite High
addiction 1 46.00 Quite Low
mu opioid receptor 1 37.84 Quite Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Overall, these results indicate that NEM treatment selectively reduced delta 1 receptor binding, resulting in a preparation that is enriched in delta 2 sites.
Negative_regulation (reduced) of 1 receptor Binding (binding) of
1) Confidence 0.04 Published 1994 Journal Receptor Section Abstract Doc Link 7950982 Disease Relevance 0 Pain Relevance 0.21
Increasingly bulky enantiomeric N-alkyl homologs were prepared until their interaction with the sigma 1 receptor decreased and their insolubility became a hindrance to their evaluation in vivo and/or in vitro.
Negative_regulation (decreased) of 1 receptor Binding (interaction) of
2) Confidence 0.02 Published 1994 Journal J. Med. Chem. Section Abstract Doc Link 7932569 Disease Relevance 0 Pain Relevance 0.42

General Comments

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