INT54805

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Context Info
Confidence 0.22
First Reported 1994
Last Reported 2008
Negated 2
Speculated 2
Reported most in Body
Documents 7
Total Number 9
Disease Relevance 4.14
Pain Relevance 1.41

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

immune system process (Ahr) cell morphogenesis (Ahr) DNA binding (Ahr)
response to stress (Ahr) cytoplasm (Ahr) signal transducer activity (Ahr)
Anatomy Link Frequency
basement membrane 1
Ahr (Rattus norvegicus)
Pain Link Frequency Relevance Heat
ketamine 136 100.00 Very High Very High Very High
corticosteroid 32 97.48 Very High Very High Very High
Inflammation 68 94.56 High High
adenocard 1 91.88 High High
anesthesia 2 84.76 Quite High
qutenza 3 84.24 Quite High
cINOD 2 75.52 Quite High
antagonist 4 75.00 Quite High
cytokine 9 74.88 Quite High
lidocaine 6 59.92 Quite High
Disease Link Frequency Relevance Heat
Asthma 253 100.00 Very High Very High Very High
Cough 47 98.76 Very High Very High Very High
Occupational Lung Diseases 25 97.96 Very High Very High Very High
INFLAMMATION 73 94.56 High High
Wheal 6 84.60 Quite High
Liver Cancer 1 78.48 Quite High
Respiratory Sounds 6 68.40 Quite High
Hypoxia 6 58.16 Quite High
Pain 5 52.24 Quite High
Fibrosis 10 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CONCLUSIONS: The computer game was a more potent stimulus than pain in countering the depressant effect of remifentanil on AHR.
Regulation (effect) of AHR
1) Confidence 0.22 Published 2005 Journal Anesthesiology Section Body Doc Link 16052121 Disease Relevance 0.10 Pain Relevance 0
On the other hand, CV-3988 had no inhibitory effect on this AHR.
Neg (no) Regulation (effect) of AHR
2) Confidence 0.21 Published 1994 Journal Res. Commun. Chem. Pathol. Pharmacol. Section Abstract Doc Link 7938906 Disease Relevance 0 Pain Relevance 0.15
AHR was defined as the provocative concentration of methacholine causing a 20% decline in FEV1 (PC20) of ?
Regulation (concentration) of AHR
3) Confidence 0.20 Published 2008 Journal Journal of Korean Medical Science Section Body Doc Link PMC2526529 Disease Relevance 0.33 Pain Relevance 0.12
Intraperitoneal injection of ketamine was set as parallel comparison in this experiments, the aim was to observe whether the effect of nebulized ketamine on OVA-induced inflammatatory changes and AHR was as effective as that of ketamine administration by systemic route.
Spec (whether) Regulation (effect) of AHR associated with asthma and ketamine
4) Confidence 0.18 Published 2007 Journal J Inflamm (Lond) Section Body Doc Link PMC1876456 Disease Relevance 0.48 Pain Relevance 0.53
RESULTS: Placebo had no effect on Vi45 or AHR over time.
Neg (no) Regulation (effect) of AHR
5) Confidence 0.13 Published 2003 Journal Anesthesiology Section Body Doc Link 14508308 Disease Relevance 0.06 Pain Relevance 0
Taken together, these findings suggest atopy may affect basement membrane thickness in asymptomatic AHR and in asthma.
Spec (may) Regulation (affect) of AHR in basement membrane associated with asthma
6) Confidence 0.12 Published 2008 Journal Journal of Korean Medical Science Section Body Doc Link PMC2526529 Disease Relevance 1.30 Pain Relevance 0.09
Since the transcription of CYP1A1 is under the control of the aryl hydrocarbon receptor (AhR), we examined the ability of sulindac to activate the receptor.
Regulation (control) of aryl hydrocarbon receptor
7) Confidence 0.12 Published 2006 Journal Carcinogenesis Section Abstract Doc Link 16531450 Disease Relevance 0.13 Pain Relevance 0.16
During the coughing period, Cth (mean log: 0.62 [95% CI: 0.43 to 0.81]) and C5 (mean log: 1.15 [95% CI: 0.86 to 1.44]) of the subjects without AHR were significantly lower (p = 0.0026, 0.027, respectively) than Cth (mean log: 1.27 [95% CI: 0.88 to 1.66]) and C5 (mean log: 1.79 [95% CI: 1.21 to 2.37]) of the subjects with AHR and those of the controls (p = 0.0002 and 0.0001).
Regulation (controls) of AHR associated with cough
8) Confidence 0.11 Published 1997 Journal Am. J. Respir. Crit. Care Med. Section Abstract Doc Link 9196099 Disease Relevance 1.56 Pain Relevance 0.16
The major advantage in using provoking stimuli that act 'indirectly' to cause airways to narrow is the high specificity for identifying the type of AHR that is altered by drugs used in the treatment of asthma [15,16], and inhaled corticosteroids in particular.
Regulation (altered) of AHR associated with asthma and corticosteroid
9) Confidence 0.10 Published 2005 Journal Respir Res Section Body Doc Link PMC1326200 Disease Relevance 0.17 Pain Relevance 0.21

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