INT54809

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Context Info
Confidence 0.14
First Reported 1994
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.31
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (TIMM13)
Anatomy Link Frequency
liver 1
TIMM13 (Homo sapiens)
Pain Link Frequency Relevance Heat
Clonidine 1 73.68 Quite High
Bioavailability 9 5.00 Very Low Very Low Very Low
Paracetamol 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Versed 1 5.00 Very Low Very Low Very Low
Potency 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ocular Hypertension 17 99.60 Very High Very High Very High
Liver Disease 4 93.88 High High
Glaucoma 5 90.00 High High
Retinal Degeneration 3 81.76 Quite High
Disease 17 74.40 Quite High
Liver Failure 2 49.92 Quite Low
Myocardial Infarction 1 13.60 Low Low
Stroke 2 12.32 Low Low
Toxicity 29 5.00 Very Low Very Low Very Low
Cancer 22 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Epinephrine 2% or 1% p-aminoclonidine lowered IOP moderately with no change in PPV, while treatment with 4% pilocarpine or 0.5% timolol reduced IOP and increased PPV significantly.
Neg (no) Regulation (change) of PPV associated with ocular hypertension
1) Confidence 0.14 Published 1994 Journal Surv Ophthalmol Section Abstract Doc Link 7940142 Disease Relevance 1.90 Pain Relevance 0.07
Very few tests have a sensitivity or specificity of 1.0 or a PPV and NPV of 1.0 but in order for a test to be useful given the demanding standards of medical practice, in this case tell us if the patient actually has liver disease, it needs to be have PPV and NPV in at least the .95 to 1.0 range.
Regulation (sensitivity) of PPV in liver associated with liver disease
2) Confidence 0.03 Published 2009 Journal Philos Ethics Humanit Med Section Body Doc Link PMC2642860 Disease Relevance 0.41 Pain Relevance 0

General Comments

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