INT5486

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Context Info
Confidence 0.21
First Reported 1992
Last Reported 1992
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 2.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Cck) extracellular region (Cck) plasma membrane (Oprd1)
cytoplasm (Oprd1) signal transducer activity (Oprd1)
Anatomy Link Frequency
substantia nigra 2
Oprd1 (Rattus norvegicus)
Cck (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Cholecystokinin 10 100.00 Very High Very High Very High
Enkephalin 8 100.00 Very High Very High Very High
opioid receptor 2 100.00 Very High Very High Very High
Substantia nigra 8 99.64 Very High Very High Very High
MU agonist 6 96.48 Very High Very High Very High
Opioid 4 75.00 Quite High
antagonist 4 62.72 Quite High
narcan 2 57.60 Quite High
Delta opioid receptors 4 31.68 Quite Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Possible interactions between Met-enkephalin and cholecystokinin (CCK)-containing neurons in the rat substantia nigra were investigated by looking for the effects of various opioid receptor ligands and inhibitors of enkephalin-degrading enzymes on the K(+)-evoked overflow of CCK-like material (CCKLM) from substantia nigra slices.
opioid receptor Regulation (effects) of CCK-like material in substantia nigra associated with substantia nigra, opioid receptor, enkephalin and cholecystokinin
1) Confidence 0.21 Published 1992 Journal J. Neurochem. Section Abstract Doc Link 1310726 Disease Relevance 0 Pain Relevance 1.08
Possible interactions between Met-enkephalin and cholecystokinin (CCK)-containing neurons in the rat substantia nigra were investigated by looking for the effects of various opioid receptor ligands and inhibitors of enkephalin-degrading enzymes on the K(+)-evoked overflow of CCK-like material (CCKLM) from substantia nigra slices.
opioid receptor Regulation (effects) of CCK in substantia nigra associated with substantia nigra, opioid receptor, enkephalin and cholecystokinin
2) Confidence 0.21 Published 1992 Journal J. Neurochem. Section Abstract Doc Link 1310726 Disease Relevance 0 Pain Relevance 1.08

General Comments

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