INT54992

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Context Info
Confidence 0.00
First Reported 1994
Last Reported 1994
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.86
Pain Relevance 0.84

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Il6, Prl) extracellular space (Il6) aging (Il6)
Anatomy Link Frequency
thyroid 1
Il6 (Rattus norvegicus)
Prl (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Neuropeptide 5 100.00 Very High Very High Very High
cytokine 3 100.00 Very High Very High Very High
Inflammation 3 100.00 Very High Very High Very High
Serotonin 1 100.00 Very High Very High Very High
rheumatoid arthritis 8 95.12 Very High Very High Very High
c fibre 1 77.84 Quite High
Neurotransmitter 1 76.48 Quite High
substance P 1 74.40 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 3 100.00 Very High Very High Very High
Rheumatoid Arthritis 8 95.12 Very High Very High Very High
Genetic Predisposition To Disease 1 88.48 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
PRL is released by the pituitary after stimulation by neuropeptides [serotonin, thyroid-releasing-hormone (TRH), or vasoactive-intestinal-peptide (VIP)], and is down-regulated by pro-inflammatory cytokines (IL-1, IL-6).
IL-6 Negative_regulation (down-regulated) of PRL in thyroid associated with inflammation, neuropeptide, serotonin and cytokine
1) Confidence 0.00 Published 1994 Journal Clin. Exp. Rheumatol. Section Abstract Doc Link 7955611 Disease Relevance 0.86 Pain Relevance 0.84

General Comments

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