INT55035

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.43
First Reported 1994
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 1.46
Pain Relevance 2.02

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il1b) aging (Il1b) extracellular region (Il1b)
Il1b (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Analgesic 8 100.00 Very High Very High Very High
qutenza 6 99.54 Very High Very High Very High
nMDA receptor antagonist 1 92.96 High High
tetrodotoxin 1 91.20 High High
antagonist 3 91.12 High High
sodium channel 1 90.28 High High
adenocard 3 86.88 High High
Hyperalgesia 2 84.44 Quite High
Hippocampus 1 81.52 Quite High
Intracerebroventricular 4 80.80 Quite High
Disease Link Frequency Relevance Heat
Hyperalgesia 10 100.00 Very High Very High Very High
Increased Venous Pressure Under Development 4 99.90 Very High Very High Very High
Nociception 6 90.24 High High
Depression 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Pretreatment with a neurotoxic dose of capsaicin reduced the capsaicin-evoked hyperaemia and prevented the facilitatory effect of interleukin-1 beta.
Negative_regulation (prevented) of Negative_regulation (effect) of interleukin-1 beta associated with qutenza and increased venous pressure under development
1) Confidence 0.43 Published 1994 Journal Eur. J. Pharmacol. Section Abstract Doc Link 7957631 Disease Relevance 0.27 Pain Relevance 0.47
An i.c.v. injection of sodium salicylate 15 min prior to interleukin-1 beta administration inhibited the hyperalgesic effect of interleukin-1 beta, but not the analgesic effect.
Negative_regulation (inhibited) of Negative_regulation (effect) of interleukin-1 beta associated with hyperalgesia and analgesic
2) Confidence 0.42 Published 1996 Journal Eur. J. Pharmacol. Section Abstract Doc Link 8741165 Disease Relevance 0.59 Pain Relevance 0.56
An i.c.v. injection of alpha-helical-corticotropin-releasing factor [9-41] 15 min prior to interleukin-1 beta administration completely blocked the hyperalgesic and analgesic effects of interleukin-1 beta.
Negative_regulation (blocked) of Negative_regulation (effects) of interleukin-1 beta associated with hyperalgesia and analgesic
3) Confidence 0.42 Published 1996 Journal Eur. J. Pharmacol. Section Abstract Doc Link 8741165 Disease Relevance 0.60 Pain Relevance 0.58
The effect of IL-1 beta on [(3)H]purine efflux was also prevented by the p38 MAP kinase inhibitor SB 203580, by the nucleoside transport inhibitor nitrobenzyl-thioinosine (NBTI) and by low temperature (4 degrees C).
Negative_regulation (prevented) of Negative_regulation (effect) of IL-1 beta
4) Confidence 0.40 Published 2004 Journal J. Neuroimmunol. Section Abstract Doc Link 15145601 Disease Relevance 0 Pain Relevance 0.42

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox