INT55070

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Context Info
Confidence 0.41
First Reported 1994
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 5
Total Number 5
Disease Relevance 3.50
Pain Relevance 2.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleolus (Ptafr) plasma membrane (Ptafr) nucleus (Ptafr)
signal transducer activity (Ptafr)
Anatomy Link Frequency
platelet 5
Ptafr (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antagonist 16 99.68 Very High Very High Very High
Inflammation 8 99.40 Very High Very High Very High
Angina 9 98.76 Very High Very High Very High
depression 9 93.52 High High
cytokine 3 92.56 High High
Inflammatory response 1 91.52 High High
Inflammatory mediators 4 90.16 High High
peptic ulcer disease 1 88.56 High High
agonist 3 80.44 Quite High
Neurotransmitter 1 71.36 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 14 99.40 Very High Very High Very High
Coronary Artery Disease 6 98.80 Very High Very High Very High
Cv General 3 Under Development 9 98.76 Very High Very High Very High
Depression 9 93.52 High High
Ulcers 3 91.68 High High
Disease 44 90.24 High High
Apoptosis 38 79.96 Quite High
Duodenal Ulcer 3 78.40 Quite High
Neurodegenerative Disease 10 53.20 Quite High
Death 4 34.20 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our results suggest that endogenous vasopressin and platelet-activating factor interact synergistically in provoking myocardial ischaemia in vivo in experimental angina in the rat.
platelet-activating factor Binding (interact) of in platelet associated with angina and coronary artery disease
1) Confidence 0.41 Published 2004 Journal Eur. J. Pharmacol. Section Abstract Doc Link 15363995 Disease Relevance 0.59 Pain Relevance 0.50
Nizatidine treatment did not significantly affect mucosal leukotriene B4, leukotriene C4 or platelet activating factor generation.
platelet activating factor Binding (generation) of in platelet
2) Confidence 0.35 Published 1994 Journal Isr. J. Med. Sci. Section Abstract Doc Link 7960687 Disease Relevance 0.64 Pain Relevance 0.21
Our results suggest that endogenous vasopressin and platelet-activating factor interact synergistically in provoking myocardial ischaemia in vivo in experimental angina in the rat.
platelet-activating factor Binding (interact) of in platelet associated with angina and coronary artery disease
3) Confidence 0.32 Published 2004 Journal Eur. J. Pharmacol. Section Abstract Doc Link 15363995 Disease Relevance 0.59 Pain Relevance 0.50
Synergistic interaction of endogenous platelet-activating factor and vasopressin in generating angina in rats.
platelet-activating factor Binding (interaction) of in platelet associated with angina
4) Confidence 0.28 Published 2004 Journal Eur. J. Pharmacol. Section Title Doc Link 15363995 Disease Relevance 0.38 Pain Relevance 0.38
The anti-inflammatory action of ginkgolides may be associated with their platelet-activating factor (PAF) -antagonist activity.
platelet-activating factor Binding (associated) of in platelet associated with inflammation and antagonist
5) Confidence 0.03 Published 2010 Journal International Journal of Molecular Sciences Section Body Doc Link PMC2820992 Disease Relevance 1.29 Pain Relevance 0.48

General Comments

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