INT55114

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Context Info
Confidence 0.58
First Reported 1994
Last Reported 2011
Negated 2
Speculated 0
Reported most in Body
Documents 42
Total Number 42
Disease Relevance 26.86
Pain Relevance 4.69

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
Nucleus 5
platelet 2
blood 2
nasal 1
lung 1
CRS (Homo sapiens)
Pain Link Frequency Relevance Heat
visual analogue scale 29 99.90 Very High Very High Very High
cytokine 46 99.44 Very High Very High Very High
Inflammation 192 99.20 Very High Very High Very High
chemokine 8 99.20 Very High Very High Very High
backache 4 99.00 Very High Very High Very High
antagonist 134 98.80 Very High Very High Very High
noradrenaline 4 97.68 Very High Very High Very High
Angina 5 96.84 Very High Very High Very High
Opioid 2 96.84 Very High Very High Very High
Inflammatory response 3 96.80 Very High Very High Very High
Disease Link Frequency Relevance Heat
Chronic Sinusitis 901 100.00 Very High Very High Very High
Syndrome 185 100.00 Very High Very High Very High
Recurrence 12 100.00 Very High Very High Very High
Pressure And Volume Under Development 40 99.84 Very High Very High Very High
Disease 386 99.76 Very High Very High Very High
Ovarian Cancer 47 99.74 Very High Very High Very High
Rhinitis 418 99.72 Very High Very High Very High
Eosinophilia 149 99.68 Very High Very High Very High
Hypersensitivity 135 99.68 Very High Very High Very High
Shock 14 99.42 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The inclusion criteria were no current symptoms of respiratory disease, no respiratory infection in the preceding 2 weeks, no allergic disease, and no other disease that could modulate CRS.
Gene_expression (modulate) of CRS in respiratory associated with hypersensitivity, lower respiratory tract infection, disease and respiratory disease
1) Confidence 0.58 Published 2008 Journal J. Physiol. Pharmacol. Section Abstract Doc Link 19218699 Disease Relevance 1.06 Pain Relevance 0.23
Need of complementary data on CRS pathogenesis
Gene_expression (pathogenesis) of CRS associated with chronic sinusitis
2) Confidence 0.48 Published 2007 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC1936288 Disease Relevance 1.00 Pain Relevance 0.14
However, in the CRS and EP1 and EP3 receptors were down-expressed compared to EP2 and EP4 and this difference was more accentuated in the CRS-NP subjects.
Gene_expression (expressed) of CRS
3) Confidence 0.43 Published 2006 Journal Respir Res Section Body Doc Link PMC1481584 Disease Relevance 0.21 Pain Relevance 0.07
protein was also statistically higher in the CRS-NP compared to CRS and in this group compared to control tissue.
Gene_expression (higher) of CRS
4) Confidence 0.42 Published 2006 Journal Respir Res Section Body Doc Link PMC1481584 Disease Relevance 0.48 Pain Relevance 0.12
While concentrations of LTC4/D4/E4, were significantly higher in CRS-NP compared to CRS and controls, no differences were observed in LTB4 levels between the groups.
Gene_expression (higher) of CRS
5) Confidence 0.42 Published 2006 Journal Respir Res Section Body Doc Link PMC1481584 Disease Relevance 0.37 Pain Relevance 0.10
In combination, these data suggest much more than simply reduced renal blood flow as an explanation for CRS.

4.2.

Gene_expression (explanation) of CRS in blood associated with syndrome
6) Confidence 0.40 Published 2011 Journal International Journal of Nephrology Section Body Doc Link PMC3021842 Disease Relevance 0.61 Pain Relevance 0.04
The percentage of CRs was on average 74.0?
Gene_expression (percentage) of CRs
7) Confidence 0.39 Published 2010 Journal Frontiers in Neuroscience Section Body Doc Link PMC2996171 Disease Relevance 0 Pain Relevance 0
Arginine vasopressin (AVP) has also detrimental effects on CRS progression by fluid retention and enhancement of angiotensin II and noradrenaline actions.
Gene_expression (progression) of CRS associated with pressure and volume under development, syndrome and noradrenaline
8) Confidence 0.39 Published 2011 Journal International Journal of Nephrology Section Body Doc Link PMC3010630 Disease Relevance 1.22 Pain Relevance 0.29
In CRS, there is no balance between NO and ROS because of the increased production of the latter.
Gene_expression (production) of CRS associated with syndrome
9) Confidence 0.39 Published 2011 Journal International Journal of Nephrology Section Body Doc Link PMC3010630 Disease Relevance 0.91 Pain Relevance 0.13
MH/TLC versus relative changes in EELV, Crs, PaCO2 and PaO2 caused by the lung recruitment maneuver
Gene_expression (changes) of Crs in lung
10) Confidence 0.35 Published 2008 Journal Crit Care Section Body Doc Link PMC2374591 Disease Relevance 0 Pain Relevance 0
We do not believe this is the main explanation, because only minor changes were found in Crs, PaO2 and PaCO2 by the LRM.
Gene_expression (found) of Crs
11) Confidence 0.35 Published 2008 Journal Crit Care Section Body Doc Link PMC2374591 Disease Relevance 0.23 Pain Relevance 0
Repeat CRS and IPCH in patients with diffuse peritoneal recurrence should be approached with caution and may be indicated only with effective second-line intraperitoneal chemotherapies.
Gene_expression (approached) of CRS associated with recurrence
12) Confidence 0.35 Published 2008 Journal Minerva Chir Section Abstract Doc Link 19078882 Disease Relevance 0.84 Pain Relevance 0.08
When made after conditioning has been established, similar interventions impair or prevent the expression of CRs [10], [12], [13], and see [14], [15] for reviews.
Gene_expression (expression) of CRs
13) Confidence 0.34 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2912226 Disease Relevance 0 Pain Relevance 0
Similarly, subjects in the Incomplete group all reached asymptote by Session 4 (Figure 3) but, during Session 2, only 2 of 6 subjects expressed any CRs.
Gene_expression (expressed) of CRs
14) Confidence 0.34 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2912226 Disease Relevance 0 Pain Relevance 0
The Cortex+Nucleus group expressed fewer CRs than the Incomplete, Nucleus Only and Off-Target groups (Kruskal-Wallis 1-way ANOVA, H?
Gene_expression (expressed) of CRs in Nucleus
15) Confidence 0.34 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2912226 Disease Relevance 0 Pain Relevance 0
In contrast, all subjects in the Control group began to express CRs on Session 2, and were asymptotic (>90% CRs) on Session 4.
Gene_expression (express) of CRs
16) Confidence 0.34 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2912226 Disease Relevance 0 Pain Relevance 0
All 4 of these subjects expressed 0% CRs at 2 and 4 hrs after muscimol, but with full recovery at 24 hrs.
Gene_expression (expressed) of CRs
17) Confidence 0.34 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2912226 Disease Relevance 0.15 Pain Relevance 0.07
In reaching a final conclusion about the distribution of plasticity across cortical and nuclear levels in eyeblink/NMR conditioning, it will be important to track down the source of these residual CRs.
Gene_expression (source) of CRs
18) Confidence 0.34 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2912226 Disease Relevance 0 Pain Relevance 0.17
All subjects Subjects in the Cortex+Nucleus group with successful, simultaneous inactivation of the cortex and nuclei immediately after each training session of Phase 1 (sessions 1–4) failed to acquire robust CRs during this Phase (see Figures 2 and 3): 3 of 4 subjects expressed no CRs during these first 4 sessions.
Neg (no) Gene_expression (expressed) of CRs in Nucleus
19) Confidence 0.29 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2912226 Disease Relevance 0 Pain Relevance 0
The Cortex+Nucleus group expressed significantly fewer CRs during Phase 1 compared to the Control, Nucleus Only, and Off-Target groups (Dunn's post hoc test, all comparisons P<0.05).
Gene_expression (expressed) of CRs in Nucleus
20) Confidence 0.29 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2912226 Disease Relevance 0 Pain Relevance 0

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