INT55193

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Context Info
Confidence 0.51
First Reported 1994
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 4
Disease Relevance 2.46
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion organization (Nrf1) nucleus (Nrf1) DNA binding (Nrf1)
cytoplasm (Nrf1)
Anatomy Link Frequency
respiratory 3
Nrf1 (Mus musculus)
Pain Link Frequency Relevance Heat
lidocaine 2 99.32 Very High Very High Very High
addiction 6 50.00 Quite Low
agonist 18 5.00 Very Low Very Low Very Low
Inflammation 6 5.00 Very Low Very Low Very Low
Paracetamol 3 5.00 Very Low Very Low Very Low
ischemia 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Shock 453 99.60 Very High Very High Very High
Stress 69 96.96 Very High Very High Very High
Injury 9 61.36 Quite High
Liver Cancer 6 41.68 Quite Low
Aging 3 25.44 Quite Low
Sprains And Strains 33 5.00 Very Low Very Low Very Low
INFLAMMATION 6 5.00 Very Low Very Low Very Low
Heat Stress Disorders 6 5.00 Very Low Very Low Very Low
Apoptosis 6 5.00 Very Low Very Low Very Low
Disease 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
HS genes linked to up-regulation of nuclear respiratory factor 1 (NRF1) were also identified (data not shown).
Regulation (regulation) of NRF1 in respiratory associated with shock
1) Confidence 0.51 Published 2010 Journal BMC Genomics Section Body Doc Link PMC2823686 Disease Relevance 0.82 Pain Relevance 0
HS genes linked to up-regulation of nuclear respiratory factor 1 (NRF1) were also identified (data not shown).
Regulation (regulation) of nuclear respiratory factor 1 in respiratory associated with shock
2) Confidence 0.51 Published 2010 Journal BMC Genomics Section Body Doc Link PMC2823686 Disease Relevance 0.82 Pain Relevance 0
NRF1 is activated by increased levels of heme and regulates a large number of genes involved in mitochondrial biogenesis and oxidative stress that overlap with those regulated by PGC-1?
Regulation (regulates) of NRF1 associated with stress
3) Confidence 0.37 Published 2010 Journal BMC Genomics Section Body Doc Link PMC2823686 Disease Relevance 0.82 Pain Relevance 0
Lidocaine and quinidine had no significant effect on the activation of the respiratory burst oxidase.
Neg (no) Regulation (effect) of respiratory burst oxidase in respiratory associated with lidocaine
4) Confidence 0.01 Published 1994 Journal Mol. Cell. Biochem. Section Abstract Doc Link 7969098 Disease Relevance 0 Pain Relevance 0.15

General Comments

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