INT55395

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Context Info
Confidence 0.42
First Reported 1994
Last Reported 1994
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Htr1a, Adra2a) signal transducer activity (Htr1a, Adra2a) signal transduction (Adra2a)
cytoplasm (Adra2a)
Htr1a (Rattus norvegicus)
Adra2a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antagonist 2 100.00 Very High Very High Very High
noradrenaline 8 98.88 Very High Very High Very High
agonist 2 96.96 Very High Very High Very High
Hippocampus 3 89.28 High High
anesthesia 1 25.00 Low Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, the common metabolite of these compounds, 1-PP (an alpha-2 adrenoceptor antagonist with low affinity for 5-HT1A receptors), also increased noradrenaline efflux whilst the 5-HT1A receptor agonist 8-OH-DPAT and MDL 73005EF, which are not metabolized to 1-PP, did not.
5-HT1A Binding (affinity) of alpha-2 adrenoceptor associated with antagonist, agonist and noradrenaline
1) Confidence 0.42 Published 1994 Journal Neuropharmacology Section Abstract Doc Link 7984279 Disease Relevance 0 Pain Relevance 0.43

General Comments

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