INT55733

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.58
First Reported 1994
Last Reported 2010
Negated 0
Speculated 1
Reported most in Abstract
Documents 47
Total Number 48
Disease Relevance 47.22
Pain Relevance 5.68

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (VTN) extracellular region (VTN) cell adhesion (VTN)
proteinaceous extracellular matrix (VTN) extracellular matrix organization (VTN)
Anatomy Link Frequency
extracellular matrix 2
ileum 1
platelet 1
coronary artery 1
superior mesenteric artery 1
VTN (Homo sapiens)
Pain Link Frequency Relevance Heat
cva 977 99.76 Very High Very High Very High
alcohol 12 98.24 Very High Very High Very High
abdominal pain 11 95.32 Very High Very High Very High
rheumatoid arthritis 5 94.64 High High
Angina 4 93.96 High High
Pain 103 93.88 High High
cytokine 15 91.44 High High
ischemia 19 87.96 High High
imagery 52 86.68 High High
beta blocker 4 82.00 Quite High
Disease Link Frequency Relevance Heat
Protein S Deficiency 20 100.00 Very High Very High Very High
Thrombophilia 2192 99.96 Very High Very High Very High
Hepatitis 6 99.92 Very High Very High Very High
Thrombosis 1169 99.86 Very High Very High Very High
Pulmonary Embolism 184 99.76 Very High Very High Very High
Coagulation Disorder 39 99.76 Very High Very High Very High
Infarction 152 99.72 Very High Very High Very High
Acquired Immune Deficiency Syndrome Or Hiv Infection 89 99.62 Very High Very High Very High
Hematological Disease 11 99.56 Very High Very High Very High
Cv Unclassified Under Development 25 99.50 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This case promotes awareness of protein S deficiency and serves as a reminder to the physician treating patients with vascular compromise and a history of human immunodeficiency virus type 1 to include protein S deficiency in the differential diagnosis.
Negative_regulation (deficiency) of protein S associated with acquired immune deficiency syndrome or hiv infection
1) Confidence 0.58 Published 2007 Journal J Am Podiatr Med Assoc Section Abstract Doc Link 17369323 Disease Relevance 1.00 Pain Relevance 0.16
A subsequent investigation revealed a mild protein S deficiency.
Negative_regulation (deficiency) of protein S
2) Confidence 0.58 Published 2008 Journal J Pak Med Assoc Section Abstract Doc Link 19157328 Disease Relevance 0.71 Pain Relevance 0.09
Protein S deficiency and lower-extremity arterial thrombosis: complicating a common presentation.
Negative_regulation (deficiency) of Protein S in extremity associated with thrombosis
3) Confidence 0.43 Published 2007 Journal J Am Podiatr Med Assoc Section Title Doc Link 17369323 Disease Relevance 0.96 Pain Relevance 0.22
After extensive inpatient vascular and hematologic work-up of this otherwise healthy woman, test results revealed that she had protein S deficiency, hepatitis C, and human immunodeficiency virus type 1.
Negative_regulation (deficiency) of protein S associated with acquired immune deficiency syndrome or hiv infection and hepatitis
4) Confidence 0.43 Published 2007 Journal J Am Podiatr Med Assoc Section Abstract Doc Link 17369323 Disease Relevance 1.05 Pain Relevance 0.21
In addition to describing this patient's evaluation and treatment, we review protein S deficiency, including its correlation with human immunodeficiency virus type 1 infection and laboratory diagnosis.
Negative_regulation (deficiency) of protein S associated with acquired immune deficiency syndrome or hiv infection and infection
5) Confidence 0.43 Published 2007 Journal J Am Podiatr Med Assoc Section Abstract Doc Link 17369323 Disease Relevance 1.03 Pain Relevance 0.19
Early coronary artery bypass graft thrombosis in a patient with protein S deficiency.
Negative_regulation (deficiency) of protein S in coronary artery associated with thrombosis
6) Confidence 0.42 Published 1996 Journal Eur J Cardiothorac Surg Section Title Doc Link 8817147 Disease Relevance 0.47 Pain Relevance 0.09
Coagulation studies two months after the acute phase of the disease revealed chronic activated coagulation with a significant protein S deficiency.
Negative_regulation (deficiency) of protein S associated with disease
7) Confidence 0.41 Published 1994 Journal Schweiz Med Wochenschr Section Abstract Doc Link 8016605 Disease Relevance 0.89 Pain Relevance 0.11
We believe this to be only the second such case of testicular infarction secondary to protein S deficiency reported in the world literature [1].
Negative_regulation (deficiency) of protein S associated with infarction
8) Confidence 0.41 Published 2006 Journal BMC Urol Section Body Doc Link PMC1543644 Disease Relevance 0.97 Pain Relevance 0.09
Acquired protein S deficiency may be seen in some patients who have developed disseminated intravascular coagulation (DIC), deep vein thrombosis (DVT) or pulmonary embolism (PE).
Negative_regulation (deficiency) of protein S in vein associated with pulmonary embolism, disseminated intravascular coagulation, cva and thrombosis
9) Confidence 0.41 Published 2006 Journal BMC Urol Section Body Doc Link PMC1543644 Disease Relevance 1.27 Pain Relevance 0.22
Protein S deficiency may be hereditary or acquired.
Negative_regulation (deficiency) of Protein S
10) Confidence 0.41 Published 2006 Journal BMC Urol Section Body Doc Link PMC1543644 Disease Relevance 1.20 Pain Relevance 0.17
The case highlights a rare but potential complication of protein S deficiency and demonstrates the importance of adequate anticoagulation in these patients.



Negative_regulation (deficiency) of protein S
11) Confidence 0.41 Published 2006 Journal BMC Urol Section Abstract Doc Link PMC1543644 Disease Relevance 0.50 Pain Relevance 0.08
The diagnosis of protein S deficiency was made in 1993, after investigation for recurrent leg ulceration, and therapy with warfarin and subsequently low molecular weight heparin commenced.
Negative_regulation (deficiency) of protein S in leg
12) Confidence 0.41 Published 2006 Journal BMC Urol Section Body Doc Link PMC1543644 Disease Relevance 1.33 Pain Relevance 0.29
It would be useful to screen these patients for Protein S deficiency and other pro-clotting conditions.


Negative_regulation (deficiency) of Protein S associated with coagulation disorder
13) Confidence 0.41 Published 2006 Journal BMC Urol Section Body Doc Link PMC1543644 Disease Relevance 1.37 Pain Relevance 0.07
Protein S deficiency is a rare blood disorder which is a risk factor for thrombophilia.
Negative_regulation (deficiency) of Protein S in blood associated with hematological disease and thrombophilia
14) Confidence 0.41 Published 2006 Journal BMC Urol Section Body Doc Link PMC1543644 Disease Relevance 0.78 Pain Relevance 0.06
Testicular infarction secondary to protein S deficiency: a case report

Background

Negative_regulation (deficiency) of protein S associated with infarction
15) Confidence 0.41 Published 2006 Journal BMC Urol Section Title Doc Link PMC1543644 Disease Relevance 0.53 Pain Relevance 0.09
Concerning the etiological factors of the thrombosis, only protein S activity definitely decreased.
Negative_regulation (decreased) of protein S associated with thrombosis
16) Confidence 0.38 Published 2007 Journal Nippon Shokakibyo Gakkai Zasshi Section Abstract Doc Link 17548950 Disease Relevance 0.68 Pain Relevance 0.08
Coagulation study showed protein S deficiency.
Negative_regulation (deficiency) of protein S
17) Confidence 0.37 Published 2004 Journal J Am Soc Echocardiogr Section Abstract Doc Link 14752493 Disease Relevance 0.50 Pain Relevance 0.16
Accurate hematological screening before reoperation showed decreased levels of protein S.
Negative_regulation (decreased) of protein S
18) Confidence 0.37 Published 1996 Journal Eur J Cardiothorac Surg Section Abstract Doc Link 8817147 Disease Relevance 0.44 Pain Relevance 0.09
This reflects a reduction in the level of protein S before the level of prothrombin is lowered into the therapeutic range.
Negative_regulation (reduction) of protein S
19) Confidence 0.36 Published 2006 Journal BMC Urol Section Body Doc Link PMC1543644 Disease Relevance 0.54 Pain Relevance 0.10
Skin necrosis has usually been reported in patients with congenital protein C deficiency or, less commonly, protein S deficiency.
Negative_regulation (deficiency) of protein S in Skin associated with necrosis
20) Confidence 0.35 Published 2004 Journal Br. J. Dermatol. Section Abstract Doc Link 15327563 Disease Relevance 0.68 Pain Relevance 0.14

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox