INT55742

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Context Info
Confidence 0.08
First Reported 1994
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.81
Pain Relevance 0.82

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Timp2) aging (Timp2) extracellular region (Timp2)
nucleus (Timp2)
Timp2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 2 99.12 Very High Very High Very High
metalloproteinase 10 98.00 Very High Very High Very High
Chronic pancreatitis 6 86.88 High High
fibrosis 1 83.00 Quite High
carpal tunnel syndrome 1 58.20 Quite High
Disease Link Frequency Relevance Heat
Dupuytren's Disease 8 100.00 Very High Very High Very High
Contracture 4 100.00 Very High Very High Very High
Fibroma 3 94.96 High High
Disease 6 88.92 High High
Pancreatitis 6 86.88 High High
Fibrosis 2 83.00 Quite High
INFLAMMATION 2 82.48 Quite High
Carpal Tunnel Syndrome 1 58.20 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
TIMP-1 and TIMP-2 could be detected in tissue of patients with Dupuytren's contracture, with an accumulation in proliferative areas.
Positive_regulation (accumulation) of Gene_expression (detected) of TIMP-2 associated with dupuytren's disease and contracture
1) Confidence 0.08 Published 2003 Journal Plast. Reconstr. Surg. Section Abstract Doc Link 14504511 Disease Relevance 1.28 Pain Relevance 0.26
The precise role of overexpression of MMP-2 and its inhibitor TIMP-2 will have to be elucidated in further studies.
Positive_regulation (overexpression) of Gene_expression (overexpression) of TIMP-2
2) Confidence 0.04 Published 1994 Journal Z Gastroenterol Section Abstract Doc Link 8017097 Disease Relevance 0.53 Pain Relevance 0.55

General Comments

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