INT55807

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Context Info
Confidence 0.42
First Reported 1994
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 4.11
Pain Relevance 0.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (GPT) small molecule metabolic process (GPT) biosynthetic process (GPT)
cellular nitrogen compound metabolic process (GPT) cytoplasm (GPT)
Anatomy Link Frequency
blood 1
thorax 1
liver 1
GPT (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 8 98.94 Very High Very High Very High
Arthritis 1 59.68 Quite High
Bile 17 53.32 Quite High
Dysuria 2 39.36 Quite Low
agonist 1 38.84 Quite Low
imagery 90 8.20 Low Low
fibrosis 7 5.00 Very Low Very Low Very Low
headache 2 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
cva 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pressure Volume 2 Under Development 2 99.48 Very High Very High Very High
Pain 6 98.94 Very High Very High Very High
Hypertension 1 98.08 Very High Very High Very High
Vomiting 6 97.50 Very High Very High Very High
Renal Disease 3 96.36 Very High Very High Very High
Lymphopenia 1 94.24 High High
Fungal Infection 10 90.88 High High
Emergencies 5 89.88 High High
Erythema 2 86.96 High High
Candida Infection 1 86.88 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The parameters associated with greater mortality were: age, absence of thoracic pain, obnubilation, hypotension, elevation in urea, GOT, GPT, LDH, decrease in prothrombin activity, pO2, pH, albumin, and the affectation of more than one lobe in a radiography of the thorax.
Negative_regulation (decrease) of GPT in thorax associated with pain and pressure volume 2 under development
1) Confidence 0.42 Published 1994 Journal Rev Clin Esp Section Abstract Doc Link 8022991 Disease Relevance 0.53 Pain Relevance 0.10
As for abnormal laboratory test, transient increases in GOT, GPT, Al-P, LDH, serum Na, Cl and decrease in serum K were observed in 9 patients (11.4%).
Negative_regulation (decrease) of GPT
2) Confidence 0.42 Published 1996 Journal Jpn J Antibiot Section Abstract Doc Link 8851308 Disease Relevance 1.37 Pain Relevance 0.10
Other AEs were reported in 20 of 234 patients, including nausea (2 patients), pain at the injection site (1), increased systolic/diastolic blood pressure (2), increased blood glucose (2), decreased white blood cell count (2), increased blood bilirubin (3), increased blood phosphorus (1), increased alanine aminotransferase (1), increased aspartate aminotransferase (1), hypertension (4), and hypotension (2).46

Effect of hepatic and renal impairment

Negative_regulation (decreased) of alanine aminotransferase in blood associated with pain, pressure volume 2 under development, hypertension and vomiting
3) Confidence 0.42 Published 2010 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2921257 Disease Relevance 0.45 Pain Relevance 0.12
Meanwhile, abnormal liver function tests revealed an alanine transaminase (ALT) level of 342I U/L (NR = 0 to 55) and alkaline phosphatase (ALP) level of 185 IU/L (NR = 40 to 150).
Negative_regulation (level) of alanine transaminase in liver
4) Confidence 0.02 Published 2010 Journal J Med Case Reports Section Body Doc Link PMC2829597 Disease Relevance 1.76 Pain Relevance 0.12

General Comments

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