INT55893

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Context Info
Confidence 0.52
First Reported 1994
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 1.04
Pain Relevance 0.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Rasa1) cell adhesion (Rasa1) plasma membrane (Rasa1)
intracellular (Rasa1) embryo development (Rasa1) cytoplasm (Rasa1)
Anatomy Link Frequency
cardiac muscle 1
striated muscle 1
Rasa1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cINOD 2 98.84 Very High Very High Very High
Inflammation 2 98.60 Very High Very High Very High
Calcium channel 5 70.68 Quite High
Neurotransmitter 1 69.28 Quite High
medulla 7 51.16 Quite High
midbrain 1 10.72 Low Low
halothane 18 5.00 Very Low Very Low Very Low
imagery 15 5.00 Very Low Very Low Very Low
tetrodotoxin 10 5.00 Very Low Very Low Very Low
sodium channel 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 2 98.60 Very High Very High Very High
Tinnitus 96 95.52 Very High Very High Very High
Congenital Anomalies 1 83.60 Quite High
Colon Cancer 6 49.68 Quite Low
Brain Injury 1 40.40 Quite Low
Deafness 15 29.56 Quite Low
Aging 1 28.36 Quite Low
Anxiety Disorder 9 5.00 Very Low Very Low Very Low
Hyperacusis 3 5.00 Very Low Very Low Very Low
Contracture 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In our previous study, we demonstrated that azoxymethane (AOM) treatment significantly enhanced the expression of ras p21, the protein product of ras genes, and that the dietary administration of chemopreventive agents such as D,L-alpha-difluoromethylornithine (DFMO), a irreversible inhibitor of ornithine decarboxylase, and piroxicam, a non-steroidal anti-inflammatory drug (NSAID), exerted a significant inhibitory effect on AOM-induced ras p21 expression.
Gene_expression (expression) of ras p21 associated with inflammation and cinod
1) Confidence 0.52 Published 1994 Journal Carcinogenesis Section Abstract Doc Link 8033306 Disease Relevance 0.10 Pain Relevance 0.15
In our previous study, we demonstrated that azoxymethane (AOM) treatment significantly enhanced the expression of ras p21, the protein product of ras genes, and that the dietary administration of chemopreventive agents such as D,L-alpha-difluoromethylornithine (DFMO), a irreversible inhibitor of ornithine decarboxylase, and piroxicam, a non-steroidal anti-inflammatory drug (NSAID), exerted a significant inhibitory effect on AOM-induced ras p21 expression.
Gene_expression (expression) of ras p21 associated with inflammation and cinod
2) Confidence 0.52 Published 1994 Journal Carcinogenesis Section Abstract Doc Link 8033306 Disease Relevance 0.09 Pain Relevance 0.14
To compensate the disadvantages of striated muscle, cardiac muscle possesses several specific properties including expression of gap junctions [26].
Gene_expression (expression) of gap in striated muscle
3) Confidence 0.13 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2850148 Disease Relevance 0 Pain Relevance 0.03
If the pre-stimulus gap is detected, there is a decreased startle reflex observed when the startle stimulus is presented (Figure 1A–B).
Gene_expression (detected) of gap
4) Confidence 0.05 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3002264 Disease Relevance 0.85 Pain Relevance 0.10
To compensate the disadvantages of striated muscle, cardiac muscle possesses several specific properties including expression of gap junctions [26].
Gene_expression (expression) of gap in cardiac muscle
5) Confidence 0.04 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2850148 Disease Relevance 0 Pain Relevance 0.03

General Comments

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