INT55898

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Context Info
Confidence 0.40
First Reported 1994
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.29
Pain Relevance 0.41

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (C4a) extracellular region (C4a) molecular_function (C4a)
Anatomy Link Frequency
platelet 2
C4a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammatory mediators 2 92.04 High High
Inflammation 22 91.28 High High
spastic colon 1 86.44 High High
Crohn's disease 2 76.08 Quite High
antagonist 1 64.80 Quite High
tetrodotoxin 1 57.20 Quite High
anesthesia 2 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
halothane 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Recurrence 19 96.80 Very High Very High Very High
Colitis 27 95.28 Very High Very High Very High
INFLAMMATION 25 91.64 High High
Disease 8 90.24 High High
Functional Bowel Disorder 1 86.44 High High
Inflammatory Bowel Disease 15 84.88 Quite High
Diarrhoea 8 5.00 Very Low Very Low Very Low
Adhesions 6 5.00 Very Low Very Low Very Low
Body Weight 6 5.00 Very Low Very Low Very Low
Fibrosis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
During mast cell degranulation, a variety of mediators are released including histamine, prostaglandin D2, leukotriene C4, platelet activating factor, heparin, and neutral proteases.
Localization (released) of C4 in platelet
1) Confidence 0.40 Published 2009 Journal Mediators of Inflammation Section Body Doc Link PMC2680139 Disease Relevance 0.96 Pain Relevance 0.19
Blockade of cyclo-oxygenase with indomethacin or of lipoxygenase with ICI 207968 or of phospholipase A2 with mepacrine inhibited release of prostaglandin E2 or leukotriene C4 or both of these plus platelet-activating factor, respectively. 4.
Localization (release) of C4 in platelet
2) Confidence 0.36 Published 1994 Journal Clin. Sci. Section Abstract Doc Link 8033515 Disease Relevance 0.33 Pain Relevance 0.22

General Comments

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