INT55960

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Context Info
Confidence 0.47
First Reported 1994
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.47
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Maob) oxidoreductase activity (Maob)
Anatomy Link Frequency
brain 2
Maob (Mus musculus)
Pain Link Frequency Relevance Heat
monoamine 10 100.00 Very High Very High Very High
medulla 2 77.92 Quite High
cerebral cortex 1 65.36 Quite High
anesthesia 1 45.36 Quite Low
Inflammation 1 26.16 Quite Low
addiction 6 5.00 Very Low Very Low Very Low
Serotonin 3 5.00 Very Low Very Low Very Low
Nicotine 2 5.00 Very Low Very Low Very Low
sSRI 2 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Nicotine Addiction 171 99.46 Very High Very High Very High
Hyperammonemia 1 95.08 Very High Very High Very High
INFLAMMATION 1 26.16 Quite Low
Atherosclerosis 3 5.00 Very Low Very Low Very Low
Lung Cancer 3 5.00 Very Low Very Low Very Low
Cancer 3 5.00 Very Low Very Low Very Low
Hypertension 2 5.00 Very Low Very Low Very Low
Obesity 2 5.00 Very Low Very Low Very Low
Cardiovascular Disorder Under Development 2 5.00 Very Low Very Low Very Low
Diabetes Mellitus 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This inhibition of MAO-B catalytic activity during smoking is also in agreement with PET-scan data obtained with brain [32] and peripheral organs [33] of smokers, non-smokers and ex-smokers using a radiotracer which binds irreversibly to MAO-B.
MAO-B Binding (binds) of in brain associated with nicotine addiction
1) Confidence 0.47 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2775922 Disease Relevance 1.37 Pain Relevance 0
Activities of monoamine oxidases, MAOA and MAOB, were measured using radiometric assays in different brain regions of the sparse-fur (spf/Y) mouse, a model of congenital hyperammonemia resulting from an X-chromosomal defect of ornithine transcarbamylase.
MAOB Binding (Activities) of in brain associated with hyperammonemia and monoamine
2) Confidence 0.37 Published 1994 Journal Neurosci. Lett. Section Abstract Doc Link 8041507 Disease Relevance 0.10 Pain Relevance 0.25

General Comments

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