INT55979

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.22
First Reported 1994
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 8
Total Number 8
Disease Relevance 2.80
Pain Relevance 1.49

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (PROC) extracellular space (PROC) extracellular region (PROC)
plasma membrane (PROC)
Anatomy Link Frequency
blood 1
cleavage 1
PROC (Homo sapiens)
Pain Link Frequency Relevance Heat
Kinase C 8 99.62 Very High Very High Very High
Inflammation 146 99.52 Very High Very High Very High
lidocaine 9 96.48 Very High Very High Very High
COX2 4 92.32 High High
Inflammatory response 23 74.36 Quite High
cINOD 18 63.20 Quite High
Parenteral administration 2 62.80 Quite High
Hippocampus 11 35.36 Quite Low
cerebral cortex 6 34.84 Quite Low
Pyramidal cell 1 18.56 Low Low
Disease Link Frequency Relevance Heat
INFLAMMATION 163 99.52 Very High Very High Very High
Poisoning 20 93.56 High High
Colon Cancer 12 88.84 High High
Apoptosis 5 88.16 High High
Disease 42 84.96 Quite High
Cancer 3 84.24 Quite High
Pressure Volume 2 Under Development 2 84.24 Quite High
Sensorineural Hearing Loss 48 78.56 Quite High
Nerve Degeneration 1 75.04 Quite High
Inflammatory Bowel Disease 94 70.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results seem to exclude the possibility of enhanced PC breakdown and further suggest that the main inhibitory effect is on the CDP-choline pathway for PC biosynthesis.
Protein_catabolism (breakdown) of PC
1) Confidence 0.22 Published 1994 Journal Cell Biochem. Funct. Section Abstract Doc Link 8044894 Disease Relevance 0 Pain Relevance 0.45
in the regulation of various pathological conditions, its effect resulting from the degradation of membrane PC.
Protein_catabolism (degradation) of PC
2) Confidence 0.05 Published 2010 Journal International Journal of Molecular Sciences Section Body Doc Link PMC2996791 Disease Relevance 0.89 Pain Relevance 0.38
Although the increased degradation of PC by cPLA2?
Protein_catabolism (degradation) of PC
3) Confidence 0.04 Published 2010 Journal International Journal of Molecular Sciences Section Body Doc Link PMC2996791 Disease Relevance 0.74 Pain Relevance 0.21
In contrast, incubation with EndoN did not remove PSA from PC but specifically degraded PSA-NCAM (Fig.
Protein_catabolism (degraded) of PC
4) Confidence 0.02 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2919383 Disease Relevance 0 Pain Relevance 0
The activated form degrades factor Va and factor VIIIa and prevents blood clots during the coagulation cascade.
Protein_catabolism (degrades) of factor VIIIa in blood
5) Confidence 0.02 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2911384 Disease Relevance 0.54 Pain Relevance 0.12
M; data not shown), indicating that PKC activation due to PC cleavage was not likely to be responsible for the inhibition of cellular vacuolation.
Protein_catabolism (cleavage) of PC in cleavage associated with kinase c
6) Confidence 0.01 Published 2008 Journal PLoS Pathogens Section Body Doc Link PMC2374909 Disease Relevance 0.21 Pain Relevance 0.18
PC-PLC cleaves PC into phosphorylcholine and diacylglycerol (DAG), which is a potent activator of protein kinase C (PKC) signaling).
Protein_catabolism (cleaves) of PC associated with kinase c
7) Confidence 0.01 Published 2008 Journal PLoS Pathogens Section Body Doc Link PMC2374909 Disease Relevance 0.09 Pain Relevance 0.15
The growth factors are released by the enzymatic degradation of the gelatin polymers after application.
Protein_catabolism (degradation) of factors
8) Confidence 0.01 Published 2010 Journal BMC Med Section Body Doc Link PMC3000370 Disease Relevance 0.33 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox