INT56084

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Context Info
Confidence 0.39
First Reported 1994
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 11
Total Number 11
Disease Relevance 5.39
Pain Relevance 2.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transmembrane transport (SLC43A3)
Anatomy Link Frequency
bands 3
neocortex 2
neuronal 1
SLC43A3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Locus ceruleus 696 99.98 Very High Very High Very High
depression 31 98.52 Very High Very High Very High
Migraine 2 93.32 High High
gABA 14 92.04 High High
Thalamus 11 87.40 High High
withdrawal 11 83.56 Quite High
cerebral cortex 20 74.76 Quite High
imagery 26 70.32 Quite High
positron emission tomography 7 56.32 Quite High
anesthesia 7 50.00 Quite Low
Disease Link Frequency Relevance Heat
Sleep Disorders 206 100.00 Very High Very High Very High
Sepsis 90 99.82 Very High Very High Very High
Partial Seizures 59 99.20 Very High Very High Very High
Depression 31 98.52 Very High Very High Very High
Convulsion 111 94.08 High High
Headache 4 93.32 High High
Increased Venous Pressure Under Development 3 92.84 High High
Heart Rate Under Development 3 92.20 High High
Sleep Initiation And Maintenance Disorders 2 88.92 High High
Encephalopathy 69 86.76 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Suppression of EEG gamma activity--an informative measure of spreading depression waves in the neocortex of the conscious rabbit.
Negative_regulation (Suppression) of EEG gamma in neocortex associated with depression
1) Confidence 0.39 Published 2006 Journal Neurosci. Behav. Physiol. Section Title Doc Link 16783516 Disease Relevance 0.80 Pain Relevance 0.40
RESULTS: Isoflurane decreased EEG activity in group 1 in a dose-related fashion.
Negative_regulation (decreased) of EEG
2) Confidence 0.36 Published 1994 Journal Anesthesiology Section Body Doc Link 8053591 Disease Relevance 0 Pain Relevance 0
[Suppression of gamma EEG activity as an index of a spreading depression wave in the neocortex of a waking rabbit].
Negative_regulation (Suppression) of EEG in neocortex associated with depression
3) Confidence 0.30 Published 2005 Journal Zh Vyssh Nerv Deiat Im I P Pavlova Section Title Doc Link 16217957 Disease Relevance 1.11 Pain Relevance 0.51
Only 21%–61% exhibit a scalp EEG correlate.36–38 This is because the neuronal hypersynchronous discharges of the simple partial seizure may remain sufficiently localized that EEG changes are attenuated between cortex and scalp.
Negative_regulation (attenuated) of EEG in neuronal associated with partial seizures
4) Confidence 0.02 Published 2010 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2898168 Disease Relevance 0.85 Pain Relevance 0.09
Thus, increases in LC activity result in increases in EEG signs of alertness [29] whilst inactivation of the LC reduces this EEG activity [30, 91], demonstrating a reduction in alertness.
Negative_regulation (reduces) of EEG associated with locus ceruleus
5) Confidence 0.02 Published 2008 Journal Current Neuropharmacology Section Body Doc Link PMC2687931 Disease Relevance 0 Pain Relevance 0.55
Thus, increases in LC activity result in increases in EEG signs of alertness [29] whilst inactivation of the LC reduces this EEG activity [30, 91], demonstrating a reduction in alertness.
Negative_regulation (reduction) of EEG associated with locus ceruleus
6) Confidence 0.02 Published 2008 Journal Current Neuropharmacology Section Body Doc Link PMC2687931 Disease Relevance 0 Pain Relevance 0.58
The present findings suggest that short episodes of drowsiness are associated with a significant amount of EEG activity in the SWA range.
Negative_regulation (amount) of EEG associated with sleep disorders
7) Confidence 0.01 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2424059 Disease Relevance 0.72 Pain Relevance 0
Spectral analysis of the EEG following sleep deprivation also revealed changes in the SWA consistent with results described in mammals.
Negative_regulation (deprivation) of EEG associated with sleep disorders
8) Confidence 0.01 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2424059 Disease Relevance 0.73 Pain Relevance 0
Generalized EEG activity tended to be reduced (increase of delta activity, decrease of activity in other frequency bands and a decrease in the main EEG frequency), but these changes did not reach the level of statistical significance.
Negative_regulation (reduced) of EEG in bands
9) Confidence 0.01 Published 2008 Journal J Neuroinflammation Section Body Doc Link PMC2553764 Disease Relevance 0.32 Pain Relevance 0.08
Generalized EEG activity tended to be reduced (increase of delta activity, decrease of activity in other frequency bands and a decrease in the main EEG frequency), but these changes did not reach the level of statistical significance.
Negative_regulation (decrease) of EEG in bands
10) Confidence 0.01 Published 2008 Journal J Neuroinflammation Section Body Doc Link PMC2553764 Disease Relevance 0.31 Pain Relevance 0.07
These findings confirm previous observations that LPS-induced sepsis in rats reduced EEG activity in frequency bands ?
Negative_regulation (reduced) of EEG in bands associated with sepsis
11) Confidence 0.01 Published 2008 Journal J Neuroinflammation Section Body Doc Link PMC2553764 Disease Relevance 0.53 Pain Relevance 0

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