INT56136

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Context Info
Confidence 0.59
First Reported 1994
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 1.99
Pain Relevance 0.67

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (IL2RB) plasma membrane (IL2RB) protein complex assembly (IL2RB)
Anatomy Link Frequency
lymphocytes 2
T-cells 1
IL2RB (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory response 2 98.98 Very High Very High Very High
Chronic pancreatitis 10 83.92 Quite High
Pain 4 81.76 Quite High
Inflammation 2 5.00 Very Low Very Low Very Low
Paracetamol 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 4 98.80 Very High Very High Very High
Solid Tumor 2 96.40 Very High Very High Very High
Chronic Disease 2 95.12 Very High Very High Very High
Marginal Zone B-cell Lymphoma 1 94.56 High High
Shock 3 91.80 High High
Apoptosis 7 88.60 High High
Pancreatitis 10 83.92 Quite High
Recurrence 4 81.12 Quite High
Pancreatic Cancer 10 79.44 Quite High
Cancer 13 50.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Inflammatory response pathway members selected in our analysis included IL2RB, carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 (CHST2), nuclear factor of activated T-cells (NFATC3), arachidonate 5-lipoxygenase (ALOX3), and pentraxin-related gene (PTX3).
Localization (sulfotransferase) of IL2RB in T-cells associated with inflammatory response
1) Confidence 0.59 Published 2008 Journal Environ Health Perspect Section Body Doc Link PMC2290973 Disease Relevance 0.37 Pain Relevance 0.05
Activated lymphocytes can release a soluble form of interleukin-2 receptor (sIL-2R) and abnormally high serum levels of sIL-2R have been reported in patients with advanced solid tumours and in those with chronic disease.
Localization (release) of interleukin-2 receptor in lymphocytes associated with solid tumor and chronic disease
2) Confidence 0.43 Published 1994 Journal Ital J Gastroenterol Section Abstract Doc Link 8061340 Disease Relevance 0.78 Pain Relevance 0.31
Activated lymphocytes can release a soluble form of interleukin-2 receptor (sIL-2R) and abnormally high serum levels of sIL-2R have been reported in patients with advanced solid tumours and in those with chronic disease.
Localization (release) of sIL-2R in lymphocytes associated with solid tumor and chronic disease
3) Confidence 0.43 Published 1994 Journal Ital J Gastroenterol Section Abstract Doc Link 8061340 Disease Relevance 0.84 Pain Relevance 0.31

General Comments

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