INT56214

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Context Info
Confidence 0.77
First Reported 1994
Last Reported 2009
Negated 0
Speculated 1
Reported most in Abstract
Documents 4
Total Number 6
Disease Relevance 4.54
Pain Relevance 0.75

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
coronary artery 1
blood 1
chest 1
Tnnt3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Angina 11 99.82 Very High Very High Very High
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 9 99.96 Very High Very High Very High
Cv General 3 Under Development 4 99.82 Very High Very High Very High
Angina 4 99.52 Very High Very High Very High
Cv Unclassified Under Development 3 99.16 Very High Very High Very High
Myocardial Infarction 15 96.34 Very High Very High Very High
Coronary Artery Disease 7 96.28 Very High Very High Very High
Acute Coronary Syndrome 9 91.44 High High
Injury 6 83.28 Quite High
Heart Disease 1 75.68 Quite High
Natriuresis 4 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We investigated whether TnT is released into circulation during severe ischaemia (e.g. on treadmill exercise testing) in patients with chronic coronary artery disease (CAD).
Localization (released) of TnT in coronary artery associated with coronary artery disease and cv unclassified under development
1) Confidence 0.77 Published 2002 Journal Acta Cardiol Section Abstract Doc Link 11918128 Disease Relevance 0.64 Pain Relevance 0.10
In conclusion, pretreatment with intravenous nicorandil suppresses TnT release after coronary angioplasty as well as ST-segment elevation during coronary angioplasty, suggesting pharmacological preconditioning by nicorandil.
Localization (release) of TnT
2) Confidence 0.69 Published 2002 Journal Jpn Heart J Section Abstract Doc Link 12452302 Disease Relevance 0.20 Pain Relevance 0.20
Our findings showed that: a) 99% of healthy blood donors had TnT concentrations < 0.10 micrograms/L; b) the test had a high clinical efficiency in the diagnosis of acute myocardial infarction, with a sensitivity of 1.0 and a specificity of 0.88 at a decision level of 0.20 micrograms/L; c) serum TnT had a later peak value (8-38 h), but a wider diagnostic window (> 126 h) than the traditional markers considered in the study; d) serum TnT had an excellent sensitivity in the detection of microinfarctions in patients with unstable angina pectoris; e) the release patterns of serum TnT were qualitatively different in perfused versus nonperfused patients.
Localization (release) of TnT in blood associated with angina and myocardial infarction
3) Confidence 0.63 Published 1994 Journal Clin. Biochem. Section Abstract Doc Link 8070069 Disease Relevance 0.80 Pain Relevance 0.35
Although both XIIaA and BNP were identified as independent predictors for all-cause mortality in the total group of patients, only BNP was found to be an independent predictor for all-cause mortality in patients with a confirmed myocardial infarction (TnT > 0.05 ng/ml) at admission (hazard ratio 4.24, 95% confidence interval 1.28-14.07), whereas only XIIaA was an independent predictor for all-cause mortality in patients with low TnT release (0.01 < TnT < or = 0.05 ng/ml) at admission (hazard ratio 10.37, 95% confidence interval 2.89-37.21).
Localization (release) of TnT associated with myocardial infarction
4) Confidence 0.10 Published 2009 Journal Blood Coagul. Fibrinolysis Section Abstract Doc Link 19809305 Disease Relevance 0.52 Pain Relevance 0
Although both XIIaA and BNP were identified as independent predictors for all-cause mortality in the total group of patients, only BNP was found to be an independent predictor for all-cause mortality in patients with a confirmed myocardial infarction (TnT > 0.05 ng/ml) at admission (hazard ratio 4.24, 95% confidence interval 1.28-14.07), whereas only XIIaA was an independent predictor for all-cause mortality in patients with low TnT release (0.01 < TnT < or = 0.05 ng/ml) at admission (hazard ratio 10.37, 95% confidence interval 2.89-37.21).
Localization (release) of TnT associated with myocardial infarction
5) Confidence 0.09 Published 2009 Journal Blood Coagul. Fibrinolysis Section Abstract Doc Link 19809305 Disease Relevance 0.53 Pain Relevance 0
Serial blood samples taken between 1 and 24 h after the onset of chest pain were analyzed for MPO, TnT, creatine kinase MB, myoglobin, and high sensitive C-reactive protein.
Spec (analyzed) Localization (creatine kinase MB) of TnT in chest associated with angina and urological neuroanatomy
6) Confidence 0.02 Published 2009 Journal Free Radic. Biol. Med. Section Abstract Doc Link 19362143 Disease Relevance 1.86 Pain Relevance 0.10

General Comments

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