INT56232

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Context Info
Confidence 0.22
First Reported 1994
Last Reported 1994
Negated 0
Speculated 1
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.33
Pain Relevance 0.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
peritoneal macrophages 2
RT1-EC2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Neuritis 7 98.12 Very High Very High Very High
antidepressant 6 93.56 High High
Endep 3 87.52 High High
Nortriptyline 2 86.92 High High
monoamine 1 75.00 Quite High
Disease Link Frequency Relevance Heat
Experimental Autoimmune Neuritis 7 98.12 Very High Very High Very High
Demyelinating Disease 1 5.00 Very Low Very Low Very Low
Autoimmune Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This study examined the modulation of IFN-gamma induced MHC class I and II expression on normal Lewis rats and rats with EAN peritoneal macrophages cultured in the absence or presence of 10(-4)-10(-8) M of the 5-HT reuptake inhibiting antidepressants zimeldine, and its metabolites norzimeldine and cpp200 oxalate as well as the antidepressants clomipramine and imipramine, in addition amitriptyline, nortriptyline and maprotiline in EAN rats.
Spec (examined) Regulation (modulation) of Spec (examined) Positive_regulation (induced) of MHC class I and II in peritoneal macrophages associated with nortriptyline, antidepressant, endep and neuritis
1) Confidence 0.22 Published 1994 Journal Immunopharmacology Section Abstract Doc Link 8071062 Disease Relevance 0.33 Pain Relevance 0.62

General Comments

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