INT56275

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Context Info
Confidence 0.01
First Reported 1994
Last Reported 1994
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.17
Pain Relevance 0.81

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (RYBP) endoplasmic reticulum (Cyp1a2) intracellular (RYBP)
enzyme binding (Cyp1a2) DNA binding (RYBP) cytoplasm (RYBP)
RYBP (Homo sapiens)
Cyp1a2 (Mus musculus)
Pain Link Frequency Relevance Heat
Paracetamol 11 100.00 Very High Very High Very High
Disease Link Frequency Relevance Heat
Hepatotoxicity 1 100.00 Very High Very High Very High
Toxicity 2 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In non-induced mice, 150 mg/kg APAP caused minimal hepatotoxicity and loss of CYP2E1- but not CYP1A2-dependent activity.
APAP Positive_regulation (caused) of Negative_regulation (loss) of CYP1A2 associated with paracetamol and hepatotoxicity
1) Confidence 0.01 Published 1994 Journal Biochem. Biophys. Res. Commun. Section Abstract Doc Link 8074700 Disease Relevance 0.17 Pain Relevance 0.81

General Comments

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