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Context Info
Confidence 0.40
First Reported 1994
Last Reported 1994
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.32
Pain Relevance 0.06

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small molecule metabolic process (CYP2B6) Golgi apparatus (TACC2) endoplasmic reticulum (CYP2B6)
microtubule organizing center (TACC2) cytoplasm (TACC2) cell proliferation (TACC2)
CYP2B6 (Homo sapiens)
TACC2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Paracetamol 2 58.16 Quite High
Disease Link Frequency Relevance Heat
Hepatitis 3 95.28 Very High Very High Very High
Hepatotoxicity 2 75.00 Quite High
Drug-induced Liver Injury 1 60.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It was identified as cytochrome P450 2C9, (P450 2C9): indeed, anti-LKM2 specifically recognized P450 2C9, but none of the other P450s tested (including other 2C subfamily members, 2C8 and 2C18).
P450 Binding (recognized) of anti-LKM2
1) Confidence 0.40 Published 1994 Journal Chem. Res. Toxicol. Section Abstract Doc Link 8075377 Disease Relevance 0.32 Pain Relevance 0.06

General Comments

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