INT56284

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Context Info
Confidence 0.56
First Reported 1994
Last Reported 2000
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 4
Disease Relevance 0.60
Pain Relevance 2.86

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (SCG2) extracellular region (SCG2) intracellular (SCG2)
Anatomy Link Frequency
uterus 1
spinal cord 1
neurons 1
cervix 1
SCG2 (Homo sapiens)
Pain Link Frequency Relevance Heat
qutenza 14 99.84 Very High Very High Very High
substantia gelatinosa 2 99.56 Very High Very High Very High
Spinal cord 20 99.28 Very High Very High Very High
substance P 4 92.48 High High
Calcitonin gene-related peptide 4 91.88 High High
medulla 2 85.68 High High
Neuropeptide 12 80.16 Quite High
Inflammation 4 75.84 Quite High
c fibre 4 75.00 Quite High
Dorsal horn 2 60.88 Quite High
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 2 80.84 Quite High
Nociception 6 76.64 Quite High
INFLAMMATION 4 75.84 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Finally, fibers in the uterus and cervix were depleted of secretoneurin by capsaicin treatment.
Negative_regulation (depleted) of secretoneurin in uterus associated with qutenza
1) Confidence 0.56 Published 2000 Journal Neuroscience Section Abstract Doc Link 10619482 Disease Relevance 0.16 Pain Relevance 0.38
Capsaicin treatment led to a marked depletion of secretoneurin-IR in the substantia gelatinosa, but not in other immunopositive areas of the spinal cord and to a substantial loss of small (< 25 microns) SgII-mRNA-containing dorsal root ganglia neurons.
Negative_regulation (depletion) of secretoneurin in neurons associated with substantia gelatinosa, qutenza and spinal cord
2) Confidence 0.43 Published 1994 Journal Eur. J. Neurosci. Section Abstract Doc Link 8075827 Disease Relevance 0.15 Pain Relevance 1.03
Radioimmunoassay revealed a significant decrease of secretoneurin-IR in the dorsal spinal cord, the trachea, heart and urinary bladder of capsaicin-treated rats.
Negative_regulation (decrease) of secretoneurin in spinal cord associated with qutenza and spinal cord
3) Confidence 0.43 Published 1994 Journal Eur. J. Neurosci. Section Abstract Doc Link 8075827 Disease Relevance 0.13 Pain Relevance 1.06
Finally, fibers in the uterus and cervix were depleted of secretoneurin by capsaicin treatment.
Negative_regulation (depleted) of secretoneurin in cervix associated with qutenza
4) Confidence 0.19 Published 2000 Journal Neuroscience Section Abstract Doc Link 10619482 Disease Relevance 0.16 Pain Relevance 0.38

General Comments

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