INT56286

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Context Info
Confidence 0.01
First Reported 1994
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 2.12
Pain Relevance 0.52

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

HLA-DRB6 (Homo sapiens)
Pain Link Frequency Relevance Heat
psoriasis 55 99.72 Very High Very High Very High
Arthritis 11 94.72 High High
Inflammation 14 92.92 High High
cytokine 19 52.08 Quite High
spinal inflammation 1 25.00 Low Low
rheumatoid arthritis 10 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
Crohn's disease 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 40 100.00 Very High Very High Very High
Psoriasis 74 99.72 Very High Very High Very High
Genetic Predisposition To Disease 1 96.24 Very High Very High Very High
Seronegative Spondarthritis 11 94.72 High High
Skin Diseases 5 93.44 High High
INFLAMMATION 14 92.92 High High
Infection 2 89.12 High High
Congenital Anomalies 1 88.56 High High
Eczema 19 86.96 High High
Arthropathy 1 70.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Genetic evidence for an (auto)immune basis of psoriasis is provided by the well-known association of the disease with the HLA-Cw6 gene [3] and the recently discovered associations with IL12B and IL23R [4], [5].
HLA-Cw6 gene Binding (association) of associated with psoriasis and disease
1) Confidence 0.01 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2649503 Disease Relevance 1.08 Pain Relevance 0.21
In psoriasis, the primary association is with HLA-Cw6.
HLA-Cw6 Binding (association) of associated with psoriasis
2) Confidence 0.00 Published 1994 Journal Baillieres Clin Rheumatol Section Abstract Doc Link 8076387 Disease Relevance 1.04 Pain Relevance 0.31

General Comments

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